中国中药杂志2025，Vol.50Issue(4)：946-958,13.DOI:10.19540/j.cnki.cjcmm.20241112.201
杜仲的化学成分、药理作用、质量控制现状及质量标志物预测分析
Review of chemical constituents,pharmacological effects,and quality control status of Eucommiae Cortex and prediction of its Q-markers
摘要
Abstract
Eucommiae Cortex,the dried bark of Eucommia ulmoides(Eucommiaceae),has both medicinal and edible values.Modern research has shown that Eucommiae Cortex contains various components such as flavonoids,lignans,iridoids,phenolic acids,terpenoids,and steroids,which have anti-osteoporosis,antioxidant,anti-inflammatory,blood glucose-lowering,and gastrointestinal tract-protecting effects.Eucommiae Cortex has applications in multiple fields such as healthcare,industry,and animal husbandry,demonstrating broad development prospects.This article reviews the chemical constituents,pharmacological effects,and quality control status of Eucommiae Cortex.Furthermore,according to the concept of quality marker(Q-marker),this article predicts the Q-markers of Eucommiae Cortex from traditional medicinal properties,traditional medicinal effects,new medicinal effects,measurability of chemical components,compatibility,harvesting periods,and geographical origins.The components such as pinoresinol diglucoside,chlorogenic acid,caffeic acid,quercetin,baicalein,baicalin,olivil,coniferyl ferulate,and kaempferol can be used as Q-markers for Eucommiae Cortex,which provide reference for establishing a systematic quality control system for Eucommiae Cortex.关键词
杜仲/化学成分/药理作用/质量控制/质量标志物Key words
Eucommiae Cortex/chemical constituent/pharmacological effect/quality control/quality marker引用本文复制引用
彭孟凡,苗明三,刘保松,闫培培,李彩霞,张小方,郑奕,宋亚刚,刘通,杨雷..杜仲的化学成分、药理作用、质量控制现状及质量标志物预测分析[J].中国中药杂志,2025,50(4):946-958,13.基金项目
国家自然科学基金项目(82204679) （82204679）
国家药品监督管理局中药安全研究与评价重点实验室开放课题(SRETCM2024-04) （SRETCM2024-04）
河南省科技攻关项目(242102310523) （242102310523）
河南省高等学校重点科研项目(25A360001) （25A360001）
驻马店市科技创新青年专项(QNZX202301) （QNZX202301）
黄淮学院博士启动基金项目(502300160174) （502300160174）
