中国卒中杂志2025，Vol.20Issue(2)：190-198,9.DOI:10.3969/j.issn.1673-5765.2025.02.009
青年非轻型缺血性卒中的影响因素及预后分析
Analysis of Influencing Factors and Prognosis of Non-Minor Ischemic Stroke in Young Adults
摘要
Abstract
Objective To explore the influencing factors and prognosis of non-tninor ischemic stroke in young adults,with the aim of reducing the rate of severe cases. Methods Young patients with ischemic stroke hospitalized in the Department of Neurology,the Second Affiliated Hospital of Naval Medical University from January 2016 to January 2022 were analyzed.According to the NIHSS score within 2 hours of the first visit,they were divided into the minor group(NIHSS score ≤3 points)and the non-minor group(NIHSS score＞3 points).The basic clinical characteristics,risk factors,TOAST classification,and 90-day outcomes of the two groups were recorded in detail,and the differences between the two groups were compared.Logistic regression analysis was used to explore the risk factors and prognostic factors of non-minor ischemic stroke in young adults. Results A total of 185 patients were included in the study,with an average age of(38.72±5.24)years and 137 males(74.05％).Among them,92 cases were in the non-minor group and 93 cases in the minor group.The proportions of risk factors were relatively high for hypertension(47.03％),smoking(41.08％),diabetes mellitus(20.54％),and hyperlipidemia(20.00％).There were statistically significant differences in the presence or absence of diabetes mellitus,heart disease,and TOAST classification between the two groups(P＜0.05).Multivariate logistic regression analysis showed that diabetes mellitus(OR 2.483,95％CI 1.076-5.726,P=0.033)and heart disease(OR 7.948,95％CI 1.691-37.367,P=0.009)were independent risk factors for non-minor ischemic stroke in young adults.Regression analysis showed that the neurological function and anxiety levels at 90 days were positively correlated with the severity of neurological function at the onset of the disease(P＜0.05). Conclusions Young people with diabetes mellitus and heart disease have a high risk of severe disease after stroke,and the prognosis is relatively poor at 90 days.Early identification and active intervention should be carried out to reduce the incidence of the disease and decrease the rate of severe cases.关键词
青年/缺血性卒中/非轻型缺血性卒中/轻型缺血性卒中/影响因素Key words
Young adult/Ischemic stroke/Non-minor ischemic stroke/Minor ischemic stroke/Influencing factor分类
临床医学引用本文复制引用
金鑫,郭笑,陈坤,龚宝峰,徐瑾..青年非轻型缺血性卒中的影响因素及预后分析[J].中国卒中杂志,2025,20(2):190-198,9.基金项目
上海卒中学会青年理事会青年创新科研启动基金项目(SSA-2020-020-6) （SSA-2020-020-6）
