中华医学杂志（英文版）2025，Vol.138Issue(2)：172-184,13.DOI:10.1097/CM9.0000000000003387
Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model
Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model
Xing Tu 1Zixing Zou 2Jiahui Li 3Simiao Zeng 3Zhengchao Luo 4Gen Li 5Yuanxu Gao 6Kang Zhang7
作者信息
- 1. Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences,Guangzhou,Guangdong 510530,China||Guangzhou National Laboratory,Guangzhou International Bio Island,Guangzhou,Guangdong 510530,China||State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangzhou,Guangdong 510623,China||University of Chinese Academy of Sciences,Beijing 100049,China
- 2. Guangzhou National Laboratory,Guangzhou International Bio Island,Guangzhou,Guangdong 510530,China
- 3. Guangzhou National Laboratory,Guangzhou International Bio Island,Guangzhou,Guangdong 510530,China||State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangzhou,Guangdong 510623,China||Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou,Guangdong 510623,China
- 4. Department of Big Data and Biomedical AI,College of Future Technology,Peking University,Beijing 100871,China
- 5. Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou,Guangdong 510623,China
- 6. Guangzhou National Laboratory,Guangzhou International Bio Island,Guangzhou,Guangdong 510530,China||Institute for Artificial Intelligence in Medicine and Faculty of Medicine,Macau University of Science and Technology,Macao Special Administrative Region 999078,China
- 7. Guangzhou National Laboratory,Guangzhou International Bio Island,Guangzhou,Guangdong 510530,China||State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University,Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science,Guangzhou,Guangdong 510623,China||Institute for Artificial Intelligence in Medicine and Faculty of Medicine,Macau University of Science and Technology,Macao Special Administrative Region 999078,China
- 折叠
摘要
关键词
Virtual screening/AI model/PANoptosis/acute ocular hypertension/HG9-91-01/GlucomaKey words
Virtual screening/AI model/PANoptosis/acute ocular hypertension/HG9-91-01/Glucoma引用本文复制引用
Xing Tu,Zixing Zou,Jiahui Li,Simiao Zeng,Zhengchao Luo,Gen Li,Yuanxu Gao,Kang Zhang..Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model[J].中华医学杂志（英文版）,2025,138(2):172-184,13.基金项目
The study was supported by grants from the Guangzhou National Laboratory(No.YW-SLJC0201),and Macao Young Scholar Program(No.AM2023024). （No.YW-SLJC0201）
