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Heterotopic ossification:Current developments and emerging potential therapies

Mingjian Bei Xinbao Wu Qiyong Cao Chunpeng Zhao Yaping Xiao Yimin Chen Honghu Xiao Xu Sun Faming Tian Minghui Yang

中华医学杂志（英文版）2025，Vol.138Issue(4)：389-404,16.

中华医学杂志（英文版）2025，Vol.138Issue(4)：389-404,16.DOI:10.1097/CM9.0000000000003244

Heterotopic ossification:Current developments and emerging potential therapies

Mingjian Bei ¹Xinbao Wu ²Qiyong Cao ¹Chunpeng Zhao ¹Yaping Xiao ³Yimin Chen ¹Honghu Xiao ¹Xu Sun ¹Faming Tian ⁴Minghui Yang¹

作者信息

1. Department of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,China
2. Department of Orthopedic Surgery,Beijing Jishuitan Hospital Affiliated to Capital Medical University,Beijing 100035,China||Beijing Research Institute of Traumatology and Orthopaedics,Beijing 100035,China
3. Department of Orthopedic Surgery,Wuhan Third Hospital,Tongren Hospital of Wuhan University,Wuhan,Hubei 430000,China
4. School Of Public Health,North China University of Science and Technology,Tangshan,Hebei 063210,China
折叠

摘要

关键词

Heterotopic ossification/Fibrodysplasia ossificans progressiva/Progressive osseous heteroplasia/Signal transduction/Endothelial-to-mesenchymal transition/Hypoxia-inducible factor 1-alpha/Small molecule inhibitors

Key words

引用本文复制引用

Mingjian Bei,Xinbao Wu,Qiyong Cao,Chunpeng Zhao,Yaping Xiao,Yimin Chen,Honghu Xiao,Xu Sun,Faming Tian,Minghui Yang..Heterotopic ossification:Current developments and emerging potential therapies[J].中华医学杂志（英文版）,2025,138(4):389-404,16.

基金项目

This work was supported by the grants from the Beijing Scholar Training Program （）

Beijing Municipal Public Wel-fare Development and Reform Pilot Project for Medical Research Institutes(Nos.JYY2023-11,JYY2023-8) （Nos.JYY2023-11,JYY2023-8）

Bei-jingJSTResearchFunding(No.2023OSR-GCZX202205) （No.2023OSR-GCZX202205）

Beijing Municipal Excellent Plan Empowerment Project(No.YC202301QX0029) （No.YC202301QX0029）

Beijing postdoctoral research Funding(No.2023-zz-008),and National Key Research and Development(R&D)Plan(No.2022YFC2504304). （No.2023-zz-008）

中华医学杂志（英文版）

ISSN：0366-6999

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