转化医学杂志2024，Vol.13Issue(11)：1889-1893,5.DOI:10.3639/j.issn.2095-3097.2024.11.019
术前全身炎症反应指数联合改良衰弱指数对胃癌根治术后并发症的预测价值
Predictive Value of Preoperative Systemic Inflammatory Response Index Combined with Modified Frailty Index for Complications after Radical Gastrectomy for Gastric Cancer
摘要
Abstract
Objective To study the predictive value of preoperative systemic inflammatory response index(SIRI)com-bined with modified frailty index(mFI-11)for complications after radical gastrectomy.Methods A retrospective analysis was conducted on the data of 150 gastric cancer patients admitted to Rugao People's Hospital from July 2015 to July 2023.All 150 patients underwent radical gastrectomy,among which 31 patients with postoperative complications were designated as the observation group,and 119 patients without complications were designated as the control group.The general information of the two groups was compared to analyze the influencing factors of postoperative complications and the predictive value of the com-bination of mFI-11 and SIRI for postoperative complications.Results The proportions of patients with ASA grade Ⅲ-Ⅳ,preoperative albumin level,mFI-11≥3 points and SIRI≥1.3 in the observation group were higher than those in the control group,and the operation time was longer than that in the control group(P<0.05).According to the Logistic regression analysis,ASA grade Ⅲ-Ⅳ,preoperative albumin,operation time,mFI-11≥3 points and SIRI≥1.3 were all risk factors for postop-erative complications(P<0.05).According to the ROC curve analysis,the predictive value of the combination of mFI-11 and SIRI for postoperative complications was higher than that of either one alone,with an AUC of 0.932,a sensitivity of 95.24％,a specificity of 88.36％,and a 95％confidence interval(95％CI)of 0.377-0.995.Conclusion ASA grade Ⅲ-Ⅳ,preoper-ative albumin,operation time,mFI-11≥3 points and SIRI≥1.3 are all risk factors for postoperative com-plications,and the combination of mFI-11 and SIRI has a high predictive value for postoperative complications,which is helpful for clinical prognosis assessment of pa-tients.关键词
术前/全身炎症反应指数/改良衰弱指数/胃癌根治术/并发症/预测价值Key words
Preoperative/Systemic Inflamma-tory Response Index/Modified Frailty Index/Radical Gastrectomy/Complications/Predictive Value分类
医药卫生引用本文复制引用
顾宏..术前全身炎症反应指数联合改良衰弱指数对胃癌根治术后并发症的预测价值[J].转化医学杂志,2024,13(11):1889-1893,5.基金项目
南通市科技局市级科技计划(指导性)(JCZ21150) （指导性）
