中南民族大学学报（自然科学版）2025，Vol.44Issue(3)：295-300,6.DOI:10.20056/j.cnki.ZNMDZK.20240723
镍催化2-氟吡啶参与的Suzuki偶联反应
Nickel-catalyzed Suzuki coupling reaction of 2-fluoropyridines
摘要
Abstract
A nickel-catalyzed Suzuki coupling reaction between 2-fluoropyridines and arylboronic acids towards the efficient synthesis of 2-arylpyridines was reported.This method exhibited advantages including simple reaction conditions,easy availability of raw materials,good yield and functional group compatibility,in which 2-fluoropyridines and aryl boronic acids substituted with different functional groups reacted easily to produce 2-arylpyridines.Based on the experimental findings and literature,a reaction mechanism was postulated.This reaction not only offered a novel approach to the synthesis of 2-arylpyridines,but also provided the possibility for obtaining 2-arylpyridine derivatives from pyridine scaffold-containing molecules with high selectivity and high yield.关键词
镍催化/2-氟吡啶/Suzuki偶联/2-芳基吡啶Key words
nickel-catalyzed/2-fluoropyridines/Suzuki coupling/2-aryl pyridines分类
化学引用本文复制引用
王子安,殷春雨,梅佳彤,张华..镍催化2-氟吡啶参与的Suzuki偶联反应[J].中南民族大学学报（自然科学版）,2025,44(3):295-300,6.基金项目
国家自然科学基金资助项目(22271313,21602096) （22271313,21602096）
