摘要
Abstract
Objective:To explore the clinical effect of Qinjiao Dihuang Tongbi Decoction in the treatment of active rheumatoid arthritis(RA)patients with damp heat accumulation toxin type.Method:A total of 60 patients with active RA with damp heat accumulation toxin type who admitted in Youxi County General Hospital from March to November 2023 were selected as the study objects,and they were randomly divided into the study group(n=30,Qinjiao Dihuang Tongbi Decoction combined with Methotrexate treatment)and the control group(30 cases,Methotrexate treatment)by random number table method.The clinical efficacy,traditional Chinese medicine syndrome score,laboratory indicators,pain level and joint disease activity in two groups were compared.Result:The total effective rate of treatment in the study group was 93.33%,which was higher than 70.00% in the control group,and the difference was statistically significant(P<0.05);after treatment,the scores of swelling,thirst,morning stiffness and heat pain in two groups were decreased,and those in the study group were lower than the control group,the differences were statistically significant(P<0.05);after treatment,the rheumatoid factor(RF),C-reactive protein(CRP)and erythrocyte sedimentation rate(ESR)in two groups were decreased,and those in the study group were lower than the control group,the differences were statistically significant(P<0.05);after treatment,the visual analogue scale(VAS)scores and 28 joint disease activity(DAS28)scores in two groups were decreased,and those in the study group were lower than the control group,the differences were statistically significant(P<0.05).Conclusion:Qinjiao Dihuang Tongbi Decoction is helpful to improve the clinical effect,improve the clinical symptoms,pain degree and joint disease activity,and reduce the levels of RF,CRP and ESR in patients with active RA with damp heat accumulation toxin type.关键词
类风湿关节炎/活动期/秦艽地黄通痹汤/湿热蕴毒型Key words
Rheumatoid arthritis/Activity period/Qinjiao Dihuang Tongbi Decoction/Damp heat accumulation toxin type