中外医学研究2025，Vol.23Issue(5)：63-67,5.DOI:10.14033/j.cnki.cfmr.2025.05.017
TC化疗方案联合贝伐珠单抗治疗晚期卵巢癌的效果
Effect of TC Chemotherapy Regimen Combined with Bevacizumab in the Treatment of Advanced Ovarian Cancer
李唯琦 1王志芳1
作者信息
- 1. 红河哈尼族彝族自治州第三人民医院 云南 个旧 661000
- 折叠
摘要
Abstract
Objective:To study the effect of Paclitaxel+Carboplatin(TC)chemotherapy regimen combined with Bevacizumab in the treatment of advanced ovarian cancer.Method:A total of 85 patients with advanced ovarian cancer who treated in the Department of Gynecology of the Third People's Hospital of Honghe Hani and Yi Autonomous Prefecture from January 2020 to January 2023 were retrospectively selected as the research objects,according to the different treatment schemes,41 patients who received TC chemotherapy regimen were classified as the control group,and 44 patients who received TC chemotherapy regimen combined with Bevacizumab were classified as the observation group.The levels of tumor markers before and after treatment,remission rate and incidence of adverse reactions were compared between two groups.Result:Before treatment,there were no significant differences in the levels of tumor markers between two groups(P>0.05);at 1 month after treatment,the levels of tumor markers in two groups were lower than those before treatment,and those in the observation group were lower than the control group,the differences were statistically significant(P<0.05).The remission rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:TC chemotherapy regimen combined with Bevacizumab can promote the decline of tumor marker levels and remission in patients with advanced ovarian cancer,and does not substantially increase the risk of adverse drug reactions.关键词
紫杉醇/卡铂/化疗/贝伐珠单抗/卵巢癌Key words
Paclitaxel/Carboplatin/Chemotherapy/Bevacizumab/Ovarian cancer引用本文复制引用
李唯琦,王志芳..TC化疗方案联合贝伐珠单抗治疗晚期卵巢癌的效果[J].中外医学研究,2025,23(5):63-67,5.
