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首页|期刊导航|中外医学研究|NT-proBNP、肌钙蛋白I及D-二聚体水平与急性心肌梗死心功能相关性研究

NT-proBNP、肌钙蛋白I及D-二聚体水平与急性心肌梗死心功能相关性研究

陈凤莲 朱青蓝 陈国飞

中外医学研究2025,Vol.23Issue(6):134-137,4.
中外医学研究2025,Vol.23Issue(6):134-137,4.DOI:10.14033/j.cnki.cfmr.2025.06.036

NT-proBNP、肌钙蛋白I及D-二聚体水平与急性心肌梗死心功能相关性研究

Study on the Relationship between NT-proBNP,Cardiac Troponin I,and D-Dimer Levels and Cardiac Function in Acute Myocardial Infarction

陈凤莲 1朱青蓝 1陈国飞1

作者信息

  • 1. 苏州市中西医结合医院 江苏 苏州 215101
  • 折叠

摘要

Abstract

Objective:To explore the association between NT-proBNP,cardiac troponin I(cTnI),and D-dimer levels and cardiac function in patients after acute myocardial infarction(AMI).Method:102 AMI patients treated at Suzhou Integrated Traditional Chinese and Western Medicine Hospital from January 2021 to December 2023 were selected and recorded as the observation group,with a concurrent control group of 102 healthy individuals.The primary biomarkers measured were NT-proBNP,cTnI,and D-dimer.Cardiac function was assessed using left ventricular ejection fraction(LVEF),cardiac output(CO),and cardiac index(CI).The relationship between biochemical markers and cardiac function indices was analyzed and evaluated.Result:In AMI patients,the average levels of NT-proBNP,cTnI,and D-dimer were significantly higher than those in the healthy control group(P<0.05).Cardiac function assessments showed that LVEF,CO,and CI were significantly lower in the observation group compared to the control group(P<0.05).Correlation analysis indicated that the levels of NT-proBNP,cTnI,and D-dimer were negatively correlated with LVEF,CO,and CI(P<0.05).Conclusion:The levels of NT-proBNP,cardiac troponin I,and D-dimer are closely associated with cardiac function impairment following acute myocardial infarction.The elevation of these biomarkers correlates with decreased cardiac function and can serve as important indicators for assessing the cardiac status of AMI patients.Monitoring these markers may help in early identification of patients with impaired cardiac function,providing guidance for clinical management.

关键词

急性心肌梗死/心功能/NT-proBNP/肌钙蛋白I/D-二聚体

Key words

Acute myocardial infarction/Cardiac function/NT-proBNP/Cardiac troponin I/D-dimer

引用本文复制引用

陈凤莲,朱青蓝,陈国飞..NT-proBNP、肌钙蛋白I及D-二聚体水平与急性心肌梗死心功能相关性研究[J].中外医学研究,2025,23(6):134-137,4.

中外医学研究

1674-6805

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