中医药信息2025，Vol.42Issue(3)：48-55,8.DOI:10.19656/j.cnki.1002-2406.20250309
基于"脾为之卫"理论探讨肠道免疫与慢性疲劳综合征的相关性
Exploring the Relationship between Intestinal Immunity and Chronic Fatigue Syndrome Based on the"Spleen Is Body's Guardian"Theory
摘要
Abstract
Chronic Fatigue Syndrome(CFS)is a multisystem disorder characterized by recurrent fatigue as the main symptom.It falls under the categories of deficiency exhaustion,depression syndrome,and Lily disease in traditional Chinese medicine.Due to its chronic and difficult-to-cure nature,CFS severely affects the patient's daily life and work.Studies have confirmed that patients with CFS exhibit various forms of intestinal immune imbalance.Based on the"Spleen Is Body's Guardian"theory,the authors propose that intestinal immunity is a modern biological interpretation of this concept.The intestinal mucosal barrier and the function of"Spleen Is Body's Guardian"share similar physiological foundations.The spleen and stomach generate defensive Qi and resist external pathogens.The strength of spleen Qi is the key to overall immune function,and a deficiency in spleen Qi results in the loss of"Spleen Is Body's Guardian",which is considered the core pathogenesis of CFS.Therefore,tonifying the spleen should be the central focus of CFS treatment,using methods such as strengthening the spleen and replenishing Qi,drying dampness,and soothing the liver to strengthen the spleen,in order to improve intestinal homeostasis and immune function.关键词
慢性疲劳综合征/脾为之卫/肠道免疫/肠道菌群Key words
Chronic fatigue syndrome/Spleen is body's guardian/Intestinal immunity/Intestinal microbiota引用本文复制引用
张晓蕾,马国海,张思宁,马紫慧,商洪涛..基于"脾为之卫"理论探讨肠道免疫与慢性疲劳综合征的相关性[J].中医药信息,2025,42(3):48-55,8.基金项目
江苏省医学会健康管理医学科研项目(SYH-32099-0120[2024024]) （SYH-32099-0120[2024024]）
江苏省中医院创新发展项目(Y2021CX17) （Y2021CX17）
