阿尔茨海默病及相关病2025，Vol.8Issue(2)：120-126,7.DOI:10.3969/j.issn.2096-5516.2025.02.008
miRNA介导的NLRP3炎性小体在阿尔茨海默病进展中的作用研究
Role of the miRNA-mediated NLRP3 inflammasome in the progression of Alzheimer's disease
摘要
Abstract
Alzheimer's disease(AD),as a neurodegenerative disease,has an abnormally complex pathogenesis and involves various biological processes.In recent years,the role of miRNA and NLRP3 inflammasome in AD,Which has been increasingly drawing attention,is becoming more and more significant.Based on the research background and significance,the article summarizes the current understanding of the role and mechanisms of miRNA-mediated NLRP3 inflammasome in the progression of AD.It is hoped that it may provide useful reference for deeply understanding the pathogenesis of AD and exploring new treatment methods as well as bring new breakthroughs for the therapy of AD.关键词
微小RNA/神经炎症/NLRP3炎性小体/阿尔茨海默病Key words
miRNA/Neuroinflammation/NLRP3/Alzheimer's disease分类
临床医学引用本文复制引用
陈肖杰,刘兰涛,赵维纳,丁明璐,王万瑶,宋一丹,霍柯源,项子瀚,王建行,陈泠羽..miRNA介导的NLRP3炎性小体在阿尔茨海默病进展中的作用研究[J].阿尔茨海默病及相关病,2025,8(2):120-126,7.基金项目
黑龙江省自然科学基金项目(SS2023H005) （SS2023H005）
黑龙江省省属高等学校基本科研费科研项目(2022-KYYWF-0662) （2022-KYYWF-0662）
牡丹江医学院附属红旗医院博士基金项目(2024-HQBS-12) （2024-HQBS-12）
牡丹江医学院研究生导师科研专项计划(YJSZX2022064) （YJSZX2022064）
