阿尔茨海默病及相关病2025，Vol.8Issue(2)：127-131,137,6.DOI:10.3969/j.issn.2096-5516.2025.02.009
APOE与甲状腺激素对阿尔茨海默病发病影响的研究进展
Research progress on the effects of APOE and thyroid hormones on the pathogenesis of Alzheimer's disease
摘要
Abstract
With the continuous exacerbation of the global aging trend,the prevalence of Alzheimer's disease(AD)is increasing year by year,significantly affecting people's quality of daily life.Among the known genetic factors causing AD,APOE is one of the more significant factors that play a crucial role in the development of AD.Additionally,abnormal levels of thyroid hormones,whether too high or too low,may have a negative impact on people's cognitive function.This impact,through a series of complex developmental mechanisms,ultimately leads to the progression of AD.Exploring the relationship between the two may find new ways to prevent or delay the progression of AD,providing better protection for the elderly population's health.关键词
阿尔茨海默病/甲状腺激素/APOE/认知功能Key words
Alzheimer's disease/Hyroid disease/APOE/Cognitive function分类
临床医学引用本文复制引用
李程杰,肖小华,梁春华,王锴锁,周艳星..APOE与甲状腺激素对阿尔茨海默病发病影响的研究进展[J].阿尔茨海默病及相关病,2025,8(2):127-131,137,6.基金项目
专2021N064基于大型队列研究和大数据技术开展阿尔茨海默病认知功能障碍的防控模式研究(KCXFZ20201221173213036) （KCXFZ20201221173213036）
深圳市医疗卫生三名工程项目资助(SZSN202311007) （SZSN202311007）
深圳市高水平医院建设专项经费资助项目 （）
