北京中医药2025,Vol.44Issue(2):132-136,5.DOI:10.16025/j.1674-1307.2025.02.004
基于营卫理论探讨IgA肾病辨治
Differentiation and treatment of IgA nephropathy based on nutrient-defense theory
都洁丽 1刘宝利 2赵启涵 2戴浩然2
作者信息
- 1. 北京中医药大学,北京 100105
- 2. 首都医科大学附属北京中医医院,北京 100010
- 折叠
摘要
Abstract
IgA nephropathy is the most common primary glomerular disease in China,with its onset closely related to mucosal immunity.Based on the nutrient-defense theory,this study explores IgA nephropathy and posits that nutrient-defense disharmony persists throughout the disease course.The specific mechanism involves nutrient-defense imbalance,with external pathogenic qi invading the muscular surface,leading to defensive qi dysfunction and nutrient qi stagnation.Internally,spleen and kidney deficiency results in the inadequate generation of nutrient and defense,causing hidden pathogens to be trapped between them.This disrupts the normal circulation of qi,blood,and body fluids.The interplay of internal and external factors leads to the accumulation of pathological substances,damage to the kidney collaterals,and ultimately the development of the disease.In clinical treatment,harmonizing nutrient and defense is proposed as the fundamental therapeutic principle,with a stage-based differentiation and treatment approach for IgA nephropathy.During the acute phase,the primary strategy is to expel pathogens and facilitate their elimination.In the chronic phase,the focus shifts to strengthening the healthy qi by warming the kidneys and invigorating the spleen.This study is expected to provide a novel perspective for the clinical treatment of IgA nephropathy with traditional Chinese medicine.关键词
IgA肾病/营卫失和/黏膜免疫/调和营卫/中医病机Key words
IgA nephropathy/nutrient-defense disharmony/mucosal immunity/harmonizing nutrient-defense/traditional Chinese medicine pathogenesis引用本文复制引用
都洁丽,刘宝利,赵启涵,戴浩然..基于营卫理论探讨IgA肾病辨治[J].北京中医药,2025,44(2):132-136,5.