国际老年医学杂志2025，Vol.46Issue(2)：156-161,6.DOI:10.3969/j.issn.1674-7593.2025.02.006
老年胃肠道肿瘤患者术后衰弱与术后恢复质量的关系研究
Study on the relationship between postoperative frailty and postoperative recovery quality in elderly patients with gastrointestinal tumor
摘要
Abstract
Objective To explore the relationship between postoperative frailty and postoperative recovery quality in elderly patients with gastrointestinal tumor,and to analyze the chain mediating effects of sleep disorders and depression on postoperative frailty and postoperative recovery quality.Methods 375 elderly patients with gastrointestinal tumor who underwent surgical treatment in the First Affiliated Hospital of Anhui Medical University from November 2021 to June 2022 as the study objects.The general information questionnaire,the Chinese Tilburg frailty scale,9-item quality of recovery score scale,sleep dysfunction rating scale,and 15-item ger-iatric depression scale were used for questionnaire investigation.Single factor and multiple linear regression were used to analyze the in-fluencing factors of postoperative recovery quality.SPSS and Bootstrap method were used to construct and verify the chain mediation model.Results Multiple linear regression analysis showed that postoperative frailty,sleep disorder and depression were independent factors affecting postoperative recovery quality in elderly patients with gastrointestinal tumors(P<0.001).The incidence of postoper-ative frailty,sleep disorder and depression were 58.7%,30.9%and 10.4%,respectively.Postoperative frailty was negatively correla-ted with postoperative recovery quality(r=-0.752,P<0.001),and was positively correlated with sleep disorders and depression(r=0.571,0.692,P<0.001).Sleep disorders was positively correlated with depression(r=0.556,P<0.001).Sleep disorders and depression were negatively correlated with postoperative recovery quality(r=-0.563,-0.634,P<0.001).The intermediary model showed that postoperative frailty directly negatively predicted postoperative recovery quality in elderly patients with gastrointestinal tumor(β=-0.567,P<0.001),and the direct effect accounted for 61.63%of the total effect.The mediating effects of sleep disor-ders,depression and sleep disorders to depression were significant(β=-0.145,-0.166,-0.042,P<0.001),accounting for 15.76%,18.04%and 4.57%of the total effect respectively.Conclusion Postoperative frailty in elderly patients with gastrointestinal tumor has a direct predictive effect on postoperative recovery quality,and is mediated by sleep disorders and depression.关键词
胃肠道肿瘤/术后衰弱/术后恢复质量/睡眠障碍/抑郁Key words
Gastrointestinal tumor/Postoperative frailty/Postoperative recovery quality/Sleep disorders/Depression引用本文复制引用
李佳佳,赵梅,王梅,马良慧..老年胃肠道肿瘤患者术后衰弱与术后恢复质量的关系研究[J].国际老年医学杂志,2025,46(2):156-161,6.基金项目
安徽医科大学护理学院研究生青苗计划培训项目(hlqm12022005) （hlqm12022005）
