国际老年医学杂志2025，Vol.46Issue(2)：185-189,5.DOI:10.3969/j.issn.1674-7593.2025.02.010
本体感觉训练联合规律有氧运动对帕金森病患者运动功能的影响
Effect of proprioceptive training combined with regular aerobic exercise on motor function in patients with Parkinson's disease
摘要
Abstract
Objective To investigate the effects of proprioceptive training combined with regular aerobic exercise on motor symptoms,cognitive function and serum BDNF level in patients with Parkinson's disease.Methods A total of 120 patients with Parkinson's disease admitted to the Third Medical Center of Chinese PLA General Hospital from January 2023 to December 2023 were selected and divided into control group(n=60)and observation group(n=60)according to simple random method(single blind method).The control group only received routine intervention,and the observation group received proprioceptive training combined with regular aerobic exercise.Motor symptoms,cognitive function,serum BDNF level were assessed before and after intervention.Re-sults The differences of TUGT time,Berg Balance Scale(BBS)score,length of movement track of pressure center and ellipse area of pressure center in observation group before and after intervention were greater than those in control group(P<0.05).After inter-vention,Montreal Cognitive Function Assessment Scale(MoCA)score,Mini-mental State Examination Scale(MMSE)score and difference of observation group were higher than those of control group(P<0.05).After intervention,the level and difference of BDNF in observation group were higher than those in control group(P<0.05).Conclusion Proprioceptive training combined with regular aerobic exercise can significantly improve motor symptoms and cognitive function in patients with Parkinson's disease,and the mecha-nism may be related to the promotion of BDNF level.关键词
帕金森病/本体感觉训练/规律有氧运动/运动症状/认知功能/脑源性神经营养Key words
Parkinson's disease/Proprioceptive training/Regular aerobic exercise/Motor symptoms/Cognitive func-tion/Brain-derived neurotrophic factor引用本文复制引用
郭建堂,刘明贺,张永青..本体感觉训练联合规律有氧运动对帕金森病患者运动功能的影响[J].国际老年医学杂志,2025,46(2):185-189,5.基金项目
国家自然科学基金面上项目(81873914) （81873914）
