国际老年医学杂志2025,Vol.46Issue(2):212-215,4.DOI:10.3969/j.issn.1674-7593.2025.02.015
肠道微生态在老年2型糖尿病患者常见微血管病变中的研究进展
Intestinal microecology and its impact on microvascular complications in elderly type 2 diabetes mellitus patients
摘要
Abstract
Type 2 diabetes mellitus(T2DM)microvascular disease encompasses pathological alterations in the growth and perme-ability of microcirculatory vessels,including arterioles,capillaries and venules,driven by prolonged hyperglycemic conditions.Microangiopa-thy represents a primary contributor to blindness,end-stage renal failure,diabetic cardiomyopathy and peripheral neuropathy in elderly T2DM patients,posing significant risks to their survival and quality of life.In recent years,the intestinal microecology has emerged as a burgeoning area of research,with numerous studies highlighting its pivotal role in influencing age-related diseases.This review synthesizes current knowl-edge on the interplay between intestinal microecology in T2DM microangiopathy,exploring potential prevention and treatment targets from an innovative perspective,and offering novel insights for the management of T2DM-related microvascular complications.关键词
2型糖尿病/微血管并发症/肠道微生态Key words
Type 2 diabetes mellitus/Microvascular complications/Intestinal microecology引用本文复制引用
陈景连,李雪萌,刘军..肠道微生态在老年2型糖尿病患者常见微血管病变中的研究进展[J].国际老年医学杂志,2025,46(2):212-215,4.基金项目
国家自然科学基金(82301752) (82301752)