中国实用神经疾病杂志2025,Vol.28Issue(3):387-391,5.DOI:10.12083/SYSJ.240708
谷氨酸转运体和神经炎症与癫痫的关系研究进展
Research progress on the relationship between glutamate transporters,neuroinflammaion and epilepsy
摘要
Abstract
Epilepsy is a neurological disease characterized by recurrent seizures.Glutamate transporters and neuroinflammation are related to the onset and development of epilepsy.The activation and lytic regulation of inflammatory cells and related factors in neuronal tissue will destroy the integrity of the blood-brain barrier,and the destruction of the integrity of the blood-brain barrier is a key factor in the development of epilepsy.This article reviews the relationship among glutamate,glutamate transporters,neuroinflammation,blood-brain barrier integrity and epilepsy,so as to provide new ideas for the prevention and treatment of epilepsy.关键词
癫痫/谷氨酸/谷氨酸转运体/神经炎症/血-脑屏障完整性Key words
Epilepsy/Glutamic acid/Glutamate transporter/Neuroinflammation/Blood-brain barrier integrity分类
临床医学引用本文复制引用
王锋,樊青俐..谷氨酸转运体和神经炎症与癫痫的关系研究进展[J].中国实用神经疾病杂志,2025,28(3):387-391,5.基金项目
青海省科技厅项目(编号:2022-ZJ-761) (编号:2022-ZJ-761)