湖南中医药大学学报2025，Vol.45Issue(3)：569-576,8.DOI:10.3969/j.issn.1674-070X.2025.03.029
药食同源植物中的生物碱抗肿瘤的研究进展
Research progress on the anti-tumor effects of alkaloids in medicinal and edible homologous plants
摘要
Abstract
Alkaloids,a class of natural organic compounds widely present in various Chinese medicinal herbs,possess complex structures,diverse types,and rich bioactive substances.They can effectively inhibit tumor growth and improve patients'quality of life,and can be used to treat chronic diseases including tumors.However,their specific anti-tumor mechanisms remain unclear.In recent years,multi-omics research technologies and analytical methods,such as genomics,transcriptomics,and metabolomics,have continuously developed and improved,providing a new cognitive path for the anti-tumor research of alkaloids in medicinal and edible homologous plants.By systematically summarizing and analyzing the anti-tumor mechanisms of alkaloids from these plants using these technologies,it is conducive to revealing the relationship between alkaloids in medicinal and edible homologous plants and the pathological processes of malignant tumors,thereby guiding the development of functional foods targeting tumor and their complications.This approach helps promote the integration and innovation of Chinese medicine and modern medicine in the fields of systems science and life omics,and also provides ideas and references for anti-tumor treatment.Based on this,this study elucidates the multi-omics integrated mechanisms of alkaloids in medicinal and edible homologous plants in anti-tumor effects,providing theoretical support for the optimization of prevention and treatment strategies for malignant tumors.关键词
药食同源/抗肿瘤/生物碱/多组学/文献计量Key words
medicinal and edible homology/anti-tumor/alkaloid/multi-omics/literature measurement分类
医药卫生引用本文复制引用
马小迪,王婧欢,聂宏,孙丹,陈着,何瑞瑞,董晓红..药食同源植物中的生物碱抗肿瘤的研究进展[J].湖南中医药大学学报,2025,45(3):569-576,8.基金项目
黑龙江省教育科学规划课题项目(2024GJB1424175) （2024GJB1424175）
黑龙江省中医药科研课题项目(ZHY2022-134) （ZHY2022-134）
黑龙江中医药大学研究生创新科研项目(2024yjscx025). （2024yjscx025）
