南京中医药大学学报2025，Vol.41Issue(3)：300-305,6.DOI:10.14148/j.issn.1672-0482.2025.0300
从代谢紊乱探讨急性胰腺炎卫气营血传变病机内涵
Exploring the Pathogenesis Connotation of Wei-Qi-Ying-Xue Transmission in Acute Pancreatitis from a Metabolic Perspec-tive
摘要
Abstract
There is a dynamic and progressive relationship in acute pancreatitis(AP),following the principle of Wei-Qi-Ying-Xue transmission in traditional Chinese medicine(TCM).The metabolic disorders prevalent in AP can be attributed to the"turbid tox-in"category in TCM,which runs throughout the disease as causative factors and pathologic products.The abnormal metabolism of sub-tle substances is the initiating factor of Wei-Qi-Ying-Xue transmission.Disorders of energy metabolism lay the pathologic basis of tur-bid evil and stagnant heat in the Qi stage of AP.Changes in the metabolic environment further exacerbate the inflammatory response re-sulting in the exuberance of pathogenic heat and the accumulation of blood stasis and toxins,promoting AP from the Qi division into the Ying-Xue stage.Therefore,we propose that"holding the Qi-fen juncture"and restoring metabolic homeostasis may be the keys to ear-ly truncation of AP disease progression.This paper explores the pathogenesis connotation of Wei-Qi-Ying-Xue transmission in AP from a metabolic perspective combined with the turbid toxin theory,which not only enriches the scientific connotation of Wei-Qi-Ying-Xue syndrome differentiation but also provides new ideas for the prevention and treatment of severe AP with TCM.关键词
急性胰腺炎/卫气营血/传变/代谢/浊毒理论/代谢重编程/代谢稳态Key words
acute pancreatitis/Wei-Qi-Ying-Xue/transmission/metabolism/turbid toxin theory/metabolic reprogramming/metabolic homeostasis分类
医药卫生引用本文复制引用
邱祺,韩晨霞,金涛,夏庆,杜丹..从代谢紊乱探讨急性胰腺炎卫气营血传变病机内涵[J].南京中医药大学学报,2025,41(3):300-305,6.基金项目
国家自然科学基金面上项目(82374256) （82374256）
四川省自然科学基金青年基金项目(2023NSFSC1755) （2023NSFSC1755）
