神经病学与神经康复学杂志2025，Vol.21Issue(1)：6-11,6.DOI:10.12022/jnnr.2024-0262
淀粉样蛋白相关影像学异常:一种与阿尔茨海默病治疗相关的具有影像学特征和诊断特异性的MRI表现
Amyloid-related imaging abnormalities:an MRI manifestation associated with Alzheimer's disease-targeted therapy with imaging characteristics and diagnostic specificity
摘要
Abstract
Amyloid-related imaging abnormalities(ARIA)are abnormal appearances on the image.In a narrow sense,the default refers specifically to abnormalities on MRI,not CT or PET.MRI findings are characteristic,including ARIA-E(edema/effusion)and ARIA-H(hemorrhage).These abnormalities occur only in patients with Alzheimer's disease(AD)and in specific disease scenarios,and are associated with β-amyloid(Aβ),which has diagnostic specificity.This article introduces the history and definition of ARIA,imaging manifestations and detection methods,severity grading of ARIA-E and ARIA-H,and clinical issues related to ARIA,in order to provide references for clinical identification and treatment of ARIA.关键词
阿尔茨海默病/β-淀粉样蛋白/淀粉样蛋白相关影像学异常/磁共振成像Key words
Alzheimer's disease/β-Amyloid/Amyloid-related imaging abnormalities(ARIA)/MRI引用本文复制引用
初曙光,王刚..淀粉样蛋白相关影像学异常:一种与阿尔茨海默病治疗相关的具有影像学特征和诊断特异性的MRI表现[J].神经病学与神经康复学杂志,2025,21(1):6-11,6.基金项目
2022年度浦东新区卫生系统学科建设项目重要薄弱学科(PWZbr2022-14) Important Weak Disciplines of Pudong New Area Health System Discipline Construction Project in 2022(PWZbr2022-14) （PWZbr2022-14）
