护理研究2025，Vol.39Issue(6)：936-940,5.DOI:10.12102/j.issn.1009-6493.2025.06.008
基于中断时间序列分析的综合防控措施对医院感染发生率变化趋势的影响
The impact of comprehensive prevention and control measures on the trend of nosocomial infection rates based on interrupted time-series analysis
摘要
Abstract
Objective:To investigate the impact of comprehensive prevention and control measures for corona virus disease 2019 on the trend of nosocomial infection rates using interrupted time-series analysis.Methods:A total of 2 301 patients with nosocomial infection from a tertiary grade A general hospital in Shanxi province were selected as subjects from February 2018 and January 2022.The period from February 2018 to January 2020 was defined as the pre-pandemic phase,and the period from February 2020 to January 2022 was defined as the pandemic control phase.The routine infection control measures was employed at the pre-pandemic phase,while comprehensive prevention and control measures for corona virus disease 2019 was employed at the pandemic control phase.Interrupted time-series analysis was used to evaluate trend of nosocomial infection rates before and after the implementation of comprehensive prevention and control measures.Results:The segmented linear regression model showed that β1=0.000,P=0.939;β2=-0.032,P=0.773;β3=-0.025,P=0.015.There was no statistically significant differences(P>0.05)in β1,β2 and β3 for the neurosurgery department and ICU.There was no statistically significant(P>0.05)in β1 and β2 for the hematology department,but there was statistical significance(P=0.008)in β3.There was statistically significant(P<0.05)in β1 and β3 for the gastrointestinal surgery,but there was no statistically significant(P=0.141)in β2.There was statistically significant(P<0.05)in β1 and β2 for the neurology department,but there was no statistically significant(P=0.271)in β3.Conclusions:Comprehensive prevention and control measures for corona virus disease 2019 exerted long-term effect on reducing nosocomial infection rates.The incidence of nosocomial infection is gradually decreasing,but variations existed across departments.关键词
医院感染/新型冠状病毒感染/疫情防控/中断时间序列分析/防控措施Key words
nosocomial infection/corona virus disease 2019/epidemic prevention and control/interrupted time-series analysis/comprehensive prevention and control measures引用本文复制引用
徐榕徽,杨晓文,陈利民..基于中断时间序列分析的综合防控措施对医院感染发生率变化趋势的影响[J].护理研究,2025,39(6):936-940,5.基金项目
山西省卫健委科研项目,编号:2021108 （）
