生殖医学杂志2025，Vol.34Issue(3)：416-420,5.DOI:10.3969/j.issn.1004-3845.2025.03.023
吲哚类物质在生殖领域的研究进展
Research progress of indoles in reproduction system
摘要
Abstract
There is growing evidence that gut microbes and their metabolites play an important role in disease susceptibility and response to diet in different individuals.Indoles produced by gut microbes metabolizing tryptophan can function as a signaling molecule,and this metabolite influences immune homeostasis by binding to aromatic hydrocarbon receptors,as well as possesses anti-inflammatory,antioxidant,and antitumor properties in the somatic circulation and,in turn,influences the compositional structure of gut microbes.In recent years,there has been a growing interest in these gut microbe-derived indole metabolites in reproductive disorders.Therefore,this article provides a review of the progress of research on indole analogs related to the reproductive system.关键词
肠道微生物/色氨酸代谢/吲哚/生殖系统Key words
Intestinal microorganisms/Tryptophan metabolism/Indole/Reproductive system分类
医药卫生引用本文复制引用
郑建秀,刘阿慧,王丽艳,金盼盼,高嘉伟,张学红..吲哚类物质在生殖领域的研究进展[J].生殖医学杂志,2025,34(3):416-420,5.基金项目
兰州大学第一医院院内基金(ldyyyn2022-20) （ldyyyn2022-20）
