天津中医药2025，Vol.42Issue(3)：337-342,6.DOI:10.11656/j.issn.1672-1519.2025.03.12
基于UPLC-Q-TOF-MS/MS技术的冠心静化学成分分析
Identification of chemical constituents in Guanxinjing based on UPLC-Q-TOF-MS/MS technology
摘要
Abstract
[Objective]To rapidly analyze and identify the chemical constituents of Guanxinjing.[Methods]Based on UPLC-Q-TOF-MS/MS technology,the chemical constituents in Guanxinjing were systematically characterized and identified by their characteristic fragments and neutral losses.[Results]A total of 96 major constituents including 29 terpenoids,29 organic acids,1 1 phthalides,13 flavonoids,and 14 other constituents were identified by compared the accurate mass measurements and secondary mass spectrometry fragment ions,and combined with the literature report and the reference.[Conclusion]This method can quickly and accurately analyze the chemical constituents of Guanxinjing,which provides a theoretical basis for the quality control and pharmacodynamic substances research of Guanxinjing.关键词
冠心静/超高效液相色谱-四极杆-飞行时间串联质谱法/化学成分/定性分析Key words
Guanxinjing/ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry/chemical constituents/qualitative analysis分类
医药卫生引用本文复制引用
刘阳,林文涵,李雯雯,任海,赵娇,欧阳慧子,何俊..基于UPLC-Q-TOF-MS/MS技术的冠心静化学成分分析[J].天津中医药,2025,42(3):337-342,6.基金项目
国家自然科学基金项目(82274091). （82274091）
