天津中医药2025，Vol.42Issue(3)：404-408,5.DOI:10.11656/j.issn.1672-1519.2025.03.20
针刺治疗慢性阻塞性肺疾病机制的研究进展
Research progress on mechanism of acupuncture treatment for chronic obstructive pulmonary disease
曹艳超 1董立鑫 2杨铭1
作者信息
- 1. 天津中医药大学第一附属医院,天津 300381||国家中医针灸临床医学研究中心,天津 300381
- 2. 天津市环湖医院,天津 300350
- 折叠
摘要
Abstract
Chronic obstructive pulmonary disease(COPD)is a chronic lung disease that occurs repeatedly and is difficult to cure.Clinical studies have shown that acupuncture can effectively relieve the clinical symptoms of COPD and improve lung function,which is an effective means to treat COPD.Clarifying the mechanism of acupuncture treatment for COPD can guide clinical practice.Through searching the basic research literature of acupuncture treatment of COPD in recent years,this paper summarized its main mechanism of action involving the following aspects:inhibiting inflammation;regulating immune cell imbalance;inhibiting oxidative stress;regulating matrix metalloproteinase-9/metalloproteinase-inhibitor-1 levels;enhancing diaphragm function;inhibiting MUC5AC(MUC5AC)expression in airway epithelial cells mediated by epidermal growth factor receptor(EGFR)-p38 mitogen activated protein kinase(p38MAPK)signaling pathway.The mechanism of acupuncture treatment of chronic obstructive pulmonary disease was expounded from the above perspectives,aiming to provide a basis for future related research.关键词
慢性阻塞性肺疾病/针刺/机制/研究进展Key words
chronic obstructive pulmonary disease/acupuncture/action mechanism/research progress分类
医药卫生引用本文复制引用
曹艳超,董立鑫,杨铭..针刺治疗慢性阻塞性肺疾病机制的研究进展[J].天津中医药,2025,42(3):404-408,5.
