新医学2025，Vol.56Issue(2)：148-154,7.DOI:10.12464/j.issn.0253-9802.2024-0446
改良甲状旁腺原位保留技术在经口腔前庭腔镜甲状腺癌根治术中的应用效果
Application effect of modified in situ parathyroid preservation technique in transoral vestibular endoscopic radical thyroidectomy for thyroid cancer
摘要
Abstract
Objective To investigate the application effect of the modified in situ parathyroid preservation technique in transoral vestibular endoscopic radical thyroidectomy for thyroid cancer.Methods A retrospective analysis was carried out on 105 patients who underwent transoral vestibular endoscopic radical thyroidectomy for thyroid cancer at Shenzhen People's Hospital from January 2020 to January 2024.The control group received traditional in situ preservation or autotransplantation of the inferior parathyroid glands,while the observation group underwent the modified in situ parathyroid preservation technique.The therapeutic effects of the two groups were compared.Results All surgeries were successfully completed in both groups.Preoperative serum calcium and parathyroid hormone(PTH)levels showed no significant differences between the observation and control groups(all P>0.05).At 24 hours postoperatively,the serum calcium in the observation group was(2.3±0.1)mmol/L,significantly higher than(2.2±0.1)mmol/L in the control group(t=-5.43,P<0.01).The PTH levels in the observation group were 18.2(5.3,28.0)pg/mL,compared to 20.8(6.8,27.1)pg/mL in the control group,with no significant difference between the two groups(t=-0.48,P>0.05).The blood calcium level in the observation group were higher than those in the control group 24 h after bilateral thyroidectomy combined with central lymph node dissection(P<0.05).The incidence of transient hypoparathyroidism was 36.7%(18/49)in the observation group and 50.0%(28/56)in the control group.At 6 weeks postoperatively,the PTH recovery rate in the observation group was 72.2%(13/18),while the control group had a PTH recovery rate of 68.2%(15/22).The difference in PTH recovery rates between the two groups was not statistically significant(P>0.05).Conclusion In transoral vestibular endoscopic radical thyroidectomy for thyroid cancer,the modified in situ parathyroid preservation technique can prevent hypoparathyroidism and contribute to the improvement of postoperative outcomes for patients.关键词
甲状旁腺保护/甲状旁腺识别/甲状旁腺损伤/甲状腺腔镜手术/甲状腺癌Key words
Parathyroid protection/Parathyroid identification/Parathyroid injury/Endoscopic thyroid surgery/Thyroid cancer引用本文复制引用
刘艳佳,许楠,王元阳,罗勋鹏..改良甲状旁腺原位保留技术在经口腔前庭腔镜甲状腺癌根治术中的应用效果[J].新医学,2025,56(2):148-154,7.基金项目
国家临床重点专科建设项目 （）
深圳市医学重点学科建设(SZXK015) （SZXK015）
