新医学2025，Vol.56Issue(2)：190-196,7.DOI:10.12464/j.issn.0253-9802.2024-0368
右美托咪定对择期剖宫产产妇术后睡眠质量及并发症的影响
Effect of dexmedetomidine on postoperative sleep quality and complications in women undergoing elective cesarean delivery
摘要
Abstract
Objective To evaluate the effect of dexmedetomidine on postoperative sleep quality and complications in women undergoing elective cesarean delivery.Methods 180 women undergoing elective cesarean delivery were selected and randomly divided into the dexmedetomidine group(group D)and control group(group C),90 cases in each group.Dexmedetomidine 0.5 μg/kg(group D)or 10 mL of 0.9%sodium chloride injection was pumped within 15 min after fetal extraction.Maternal sleep status was assessed by Pittsburgh Sleep Quality Index(PSQI)and Insomnia Severity Index(ISI)for 24 h,48 h postoperatively and 1 day before discharge.Maternal resting pain and activity-induced pain at 24 h and 48 h postoperatively were recorded by visual analog score(VAS)in both groups.Other perioperative complications of labor were recorded.Results The PSQI scores and ISI scores of the women in group D were lower than those of the women in group C at 24 h,48 h after surgery and 1 day before discharge(all P<0.05).The incidence of severe sleep disorders and insomnia at 24 h postoperatively was lower in group D than that in group C(P=0.031 and P=0.021).The women in group D had less resting pain and activity-induced pain at 24 h and 48 h postoperatively,and the number of postoperative PCEA compressions was also lower(all P<0.05).The incidence of postoperative nausea and vomiting,itchy skin complications was lower in group D.The time to first postoperative activity,the length of postoperative hospital stay was shorter,degree of satisfaction during hospitalization was higher,and the incidence of depression at 6 weeks postpartum was also lower(all P<0.05).Conclusion Dexmedetomidine improves sleep quality after cesarean delivery,reduces postoperative pain and complications.关键词
右美托咪定/剖宫产/睡眠障碍/术后疼痛/产后抑郁/并发症Key words
Dexmedetomidine/Cesarean delivery/Sleep disorder/Postoperative pain/Postpartum depression/Complications引用本文复制引用
游意莹,钟伟龙,王艳玲,李利平..右美托咪定对择期剖宫产产妇术后睡眠质量及并发症的影响[J].新医学,2025,56(2):190-196,7.基金项目
广东省自然科学基金(2023A1515010288) （2023A1515010288）
