医疗卫生装备2025，Vol.46Issue(3)：48-53,6.DOI:10.19745/j.1003-8868.2025047
剂量表面积直方图对宫颈癌图像引导放疗致急性放射性直肠炎的预测价值
Predictive value of dose surface histogram for acute radiation proctitis induced by image guided radiotherapy for cervical cancer
摘要
Abstract
Objective To explore the predictive value of dose surface histogram(DSH)in image guided radiotherapy(IGRT)for radiotherapy-induced acute radiation proctitis(ARP)in cervical cancer(CCA).Methods Totally 380 patients with CCA IGRT admitted to some hospital from May 2019 to May 2023 were selected prospectively and randomly divided into a control group(n=1 80)and an experimental group(n=200).The patients in the 2 groups were followed up and the incidence rates of ARP were counted,and rectal dose distribution was evaluated using dose volume histogram(DVH)in the control group and DSH in the experimental group.The predictive values of DVH and DSH for ARP were evaluated and compared using ROC curves.Statistical analysis was performed using SPSS 21.0 software.Results The two groups did not have statistically significant difference in the incidence rate of ARP(P＞0.05),while there were significant differences in the evaluation indicators of the rectal dose distribution(P＜0.05).V40,V50,S40 and S50 proved to have low predictive values for grade Ⅰ-Ⅳ ARP with AUC 0.700(P＜0.05);V60 and S60 had moderate predictive values for grade Ⅰ-Ⅳ ARP with AUC greater than 0.700 and less than or equal to 0.900(P＜0.05);V70,V78,S70 and S7s showed high predictive values for grade Ⅰ-Ⅳ ARP with AUC higher than 0.900(P＜0.05).Delong's test results indicated that DVH and DSH had no significant differences in AUC when used to predict gradeⅠ-Ⅳ ARP(allP＞0.05).Conclusion DSH is essentially the same as DVH when used for the prediction of grade Ⅰ-Ⅳ ARP due to CCA IGRT,and thus can be used for the supplementation and optimization of radiotherapy planning systems.[Chinese Medical Equipment Journal,2025,46(3):48-53]关键词
宫颈癌/图像引导放疗/剂量表面积直方图/急性放射性直肠炎/剂量体积直方图Key words
cervical cancer/image guided radiotherapy/dose surface histogram/acute radiation proctitis/dose volume histogram分类
医药卫生引用本文复制引用
刘庆啸,朱月香,魏伟,田龙,杨松林,王晸,赵御森,王素丽,常茂叶..剂量表面积直方图对宫颈癌图像引导放疗致急性放射性直肠炎的预测价值[J].医疗卫生装备,2025,46(3):48-53,6.基金项目
张家口市重点研究计划项目(2421018D) （2421018D）
