中国肺癌杂志2025，Vol.28Issue(2)：95-104,10.DOI:10.3779/j.issn.1009-3419.2025.102.03
非小细胞肺癌三级淋巴结构评估及临床应用中国专家共识(2025版)
Chinese Expert Consensus on Assessment and Clinical Application of Tertiary Lymphoid Structure for Non-small Cell Lung Cancer(2025 Version)
中国抗癌协会肿瘤病理专业委员会肺癌协作组 1中国临床肿瘤学会非小细胞肺癌专业委员会 1林冬梅 1周彩存 1李媛 1沈波1
作者信息
摘要
Abstract
The tertiary lymphoid structure(TLS)plays a crucial role in the tumor microenvironment,influenc-ing tumor development and progression.As an emerging biomarker for predicting the prognosis and treatment response in cancer patients,TLS has received increasing attention.However,there is currently a lack of standardized evaluation criteria for TLS,and significant differences exist in TLS across different tumor tissues.This poses challenges for the clinical application of this biomarker in translation.To meet the clinical diagnosis and treatment needs of non-small cell lung cancer(NSCLC),this consensus focuses on the definition,clinical significance,testing components,and assessment methods of TLS in NSCLC.Combining relevant research and Chinese clinical practice,it provides standardized and normalized suggestions for the clinical assessment and application of TLS,so as to improve the understanding of TLS among clinicians and pathologists,and provide a reference basis for the clinical application of the detection of TLS in NSCLC.关键词
肺肿瘤/三级淋巴结构/评估/临床应用/共识Key words
Lung neoplasms/Tertiary lymphoid structure/Assessment/Clinical application/Consensus引用本文复制引用
中国抗癌协会肿瘤病理专业委员会肺癌协作组,中国临床肿瘤学会非小细胞肺癌专业委员会,林冬梅,周彩存,李媛,沈波..非小细胞肺癌三级淋巴结构评估及临床应用中国专家共识(2025版)[J].中国肺癌杂志,2025,28(2):95-104,10.
