中国康复理论与实践2025，Vol.31Issue(3)：365-372,8.DOI:10.3969/j.issn.1006-9771.2025.03.014
胼胝体梗死的康复效果评估:基于功能近红外光谱技术的个案研究
Assessment of rehabilitation of corpus callosum infarction:a case report based on functional near infrared spec-troscopy
摘要
Abstract
Objective To report the individualized rehabilitation protocol administered to a patient suffering from corpus callosum injury subsequent to cerebral infarction,manifesting clinically as alien hand syndrome,attention deficits,spatial neglect and gait apraxia;and to emphasize the application of functional near infrared spectroscopy(fNIRS)in the assessment of cerebral activation. Methods A 54-year-old male with corpus callosum damage following cerebral infarction was assessed by a comprehen-sive array of neuropsychological assessments,such as Mini-Mental State Examination,Montreal Cognitive As-sessment,Loewenstein Occupational Therapy Cognitive Assessment and Wisconsin Card Sorting Test,etc.Based on these assessments,a personalized rehabilitation program was devised,incorporating physical therapy,occupa-tional therapy,task-oriented training,mirror therapy,computer-assisted cognitive training,as well as Schulte's square attention training,bilateral limb coordination training and transcranial magnetic stimulation(TMS).fNIRS was used to evaluate changes in brain activation before and after rehabilitation. Results After more than a month of comprehensive rehabilitation,the patient experienced significant improvements in Alien hand syndrome,attention deficit and spatial neglect.Gait was normalized,and enhancements were ob-served in motor function,cognition and activity of daily living.fNIRS analysis revealed favorable alterations in cerebral activation patterns. Conclusion For the intricate symptoms associated with corpus callosum injury,a multidisciplinary rehabilitation ap-proach,particularly the incorporation of Schulte's square attention training,bilateral coordination exercises and TMS,alongside fNIRS for monitoring cerebral activation,showed significant rehabilitation effects.关键词
脑梗死/胼胝体/康复/经颅磁刺激/功能近红外光谱技术Key words
cerebral infarction/corpus callosum/rehabilitation/transcranial magnetic stimulation/functional near infrared spectroscopy分类
临床医学引用本文复制引用
陈予东,杜晓霞,黄富表,叶长青,马琳,王云雷,吴晓莉..胼胝体梗死的康复效果评估:基于功能近红外光谱技术的个案研究[J].中国康复理论与实践,2025,31(3):365-372,8.基金项目
中国康复研究中心青年课题(No.2023ZX-Q4) Supported by China Rehabilitation Research Center Project(Youth)(No.2023ZX-Q4) （No.2023ZX-Q4）
