中国食品药品监管Issue(2)：104-111,8.DOI:10.3969/j.issn.1673-5390.2025.02.010
基于高分辨质谱的非靶向筛查技术在化妆品安全性风险物质监管中的应用前景
Application Prospects of Non-Targeted Screening Technology Based on High-Resolution Mass Spectrometry in the Regulation of Safety Risk Substances in Cosmetics
摘要
Abstract
Safety risk substances present in cosmetics can pose potential threats to human health,making strict component analysis essential.Traditional analysis methods primarily rely on targeted analysis based on known risk substances,which makes it difficult to effectively detect unknown hazards.In contrast,non-targeted screening technology based on high-resolution mass spectrometry is characterized by high sensitivity,high resolution,and high precision,enabling comprehensive and rapid detection of unknown risk substances in cosmetics.This paper details the technical advantages,workflow,application cases,and future development trends of the non-targeted screening method in the supervision of cosmetic safety risk substances.It is anticipated that further development and application of non-targeted screening methods will significantly enhance the safety and quality reliability of cosmetics,thereby providing stronger health and safety protection for consumers.关键词
非靶向筛查/高分辨质谱/化妆品/安全性风险物质/分子网络Key words
non-targeted screening/high-resolution mass spectrometry/cosmetics/safety risk substances/molecular networking分类
医药卫生引用本文复制引用
郭栋,梁静文,李杨杰,尹胜,方继辉..基于高分辨质谱的非靶向筛查技术在化妆品安全性风险物质监管中的应用前景[J].中国食品药品监管,2025,(2):104-111,8.基金项目
广东省药品监督管理局2023年度科技创新项目(ZA20230069) （ZA20230069）
广东省省级科技计划项目(2023A1111120025) （2023A1111120025）
广东省药品监督管理局2024年度科技创新项目(2024ZDZ04) （2024ZDZ04）
