中国实用内科杂志2025，Vol.45Issue(3)：199-203,209,6.DOI:10.19538/j.nk2025030105
糖尿病肾脏疾病诊疗中需要关注的几个问题
Some issues deserving attention in the diagnosis and treatment of diabetic kidney disease
摘要
Abstract
There are some issues that are often neglected by clinicians in clinical diagnosis and treatment of diabetic kidney disease(DKD).Firstly,the definitions of diabetic nephropathy(DN),DKD,and diabetes mellitus in chronic kidney disease(DM in CKD)should be clarified.DN is characterized by kidney-specific histopathological changes due to DM,which is confirmed by biopsy.DKD,used for non-biopsy clinical diagnosis,is widely applied at present,while DMinCKD includes all CKD types in DM patients.Secondly,renal function in DKD patients usually declines slowly,but some patients experience continuous eGFR decline[＞7 ml/(min·1.73 m2)per year or＞4％per year],which presents as rapidly progressive type,and hematuria often occurs in patients with interstitial inflammation.DKD crescents,different from inflammatory crescents,may be formed during the self-repair process of injured glomerular cells differentiating into podocytes,and the prognosis is poor.Enhanced recognition of these issues is crucial for improving DKD's prevention and management.关键词
糖尿病肾脏疾病/快速进展型糖尿病肾病/血尿/新月体Key words
diabetic kidney disease/rapidly progressive diabetic nephropathy/hematuria/crescents分类
临床医学引用本文复制引用
陈晓君,孙林..糖尿病肾脏疾病诊疗中需要关注的几个问题[J].中国实用内科杂志,2025,45(3):199-203,209,6.基金项目
湖南省自然科学基金委员会重大揭榜项目(2021JC0003) （2021JC0003）
