中国药物经济学2025，Vol.20Issue(2)：82-84,92,4.DOI:10.12010/j.issn.1673-5846.2025.02.016
右美托咪定对老年患者预防术后躁动发生的影响
Effect of Dexmedetomidine on Prevention of Postoperative Agitation in Elderly Patients
吴旭 1王雷 2周蕾 1李金燕 1汤新1
作者信息
- 1. 大连大学附属中山医院麻醉科,辽宁 大连 116001
- 2. 中国人民解放军联勤保障部队第九六七医院骨科,辽宁 大连 116000
- 折叠
摘要
Abstract
Objective To exolore the effect of dexmedetomidine on prevention of postoperative agitation in elderly patients.Methods Sixty elderly patients with fracture admitted to Zhongshan Hospital Affiliated to Dalian University from January 2022 to December 2023 were randomly divided into experimental group and control group,with 30 cases in each group.The control group received general anesthesia surgery,and the experimental group received dexmedetomidine combined intervention based on the control group.Heart rate(HR),mean arterial pressure(MAP),blood oxygen saturation(SpO2)before and 2 h after surgery,postoperative recovery and recovery,agitation score,postoperative pain score,incidence of adverse reactions during recovery and satisfaction with anesthesia were compared between the two groups.Results There was no significant difference in vital signs between the two groups before surgery(P＞0.05).2 h after operation,HR,MAP and SpO2 in experimental group were higher than those in control group(P＜0.05).The anesthesia recovery time of experimental group was shorter than that of control group(P＜0.05),and the dosage of remifentanil was shorter than that of control group(P＜0.05).The score of agitation in experimental group was lower than that in control group(P＜0.05),the score of visual analogue scale(VAS)after surgery was lower than that in control group(P＜0.05),and the incidence of adverse reactions during recovery was lower than that in control group(P＜0.05).The satisfaction of anesthesia in experimental group was higher than that in control group(P＜0.05).Conclusion Dexmedetomidine anesthesia in elderly patients with fracture can significantly improve the changes of patients'vital signs during surgery,accelerate postoperative recovery and recovery,relieve pain,reduce the incidence of postoperative agitation,and improve anesthesia satisfaction.关键词
右美托咪定/老年患者/骨折/术后躁动Key words
Dexmedetomidine/Elderly patients/Fracture/Postoperative agitation分类
医药卫生引用本文复制引用
吴旭,王雷,周蕾,李金燕,汤新..右美托咪定对老年患者预防术后躁动发生的影响[J].中国药物经济学,2025,20(2):82-84,92,4.
