中国中西医结合影像学杂志2025，Vol.23Issue(2)：208-211,222,5.DOI:10.3969/j.issn.1672-0512.2025.02.014
基于CT增强扫描影像组学联合临床模型对腮腺多形性腺瘤与腺淋巴瘤的鉴别诊断
A CT radiomics-clinical integrated model for distinguishing pleomorphic adenoma from Warthin tumor
摘要
Abstract
Objective:To explore the value of enhanced CT-based radiomics combined clinical model in the differential diagnosis of pleomorphic adenoma(PA)from Warthin tumor(WT)in the parotid gland.Methods:This retrospective study analyzed 90 PA patients and 70 WT patients.Univariate analysis was used for clinical data selecting,while univariate rank sum test,correlation analysis and LASSO algorithm were used for radiomics features screening.The combined model was established by the selected optimal radiomics model and clinical data.All patients were randomly divided into a training cohort(112 cases)and a validation cohort(48 cases)at a 7∶3 ratio.The ROC curves were used to evaluate the predictive efficacies of each model.Results:The AUC was 0.889(95%CI 0.812-0.966)for clinical model,including sex,age,smoking history and lesion number.Five,four and five radiomics features of arterial-phase,venous-phase and the two-phase combined models were used to establish the radiomics models.The optimal radiomics model was the two-phase combined model,with the AUC of 0.951(95%CI 0.890-1.000).Ultimately the clinical data was added to the optimal radiomic model,the AUC was 0.969(95%CI 0.922-1.000),which was better than that of other models.Conclusions:The combination of arterial-and venous-phase radiomics model is superior to other radiomics models in differentiating PA and WT,and the combined model constructed by the optimal radiomics model and clinical model had a high differential value.关键词
多形性腺瘤/腺淋巴瘤/腮腺肿瘤/影像组学/体层摄影术,X线计算机Key words
Pleomorphic adenoma/Warthin tumor/Parotid tumor/Radiomics/Tomography,X-ray computed引用本文复制引用
路丽,柳成良,张力,左超,于淑靖..基于CT增强扫描影像组学联合临床模型对腮腺多形性腺瘤与腺淋巴瘤的鉴别诊断[J].中国中西医结合影像学杂志,2025,23(2):208-211,222,5.基金项目
河北省医学科学研究课题计划资助(20220378). （20220378）
