中国中西医结合影像学杂志2025，Vol.23Issue(2)：223-227,5.DOI:10.3969/j.issn.1672-0512.2025.02.017
Ⅰ期浸润性非黏液性肺腺癌的CT特征与病理亚型的相关性研究
Correlations between CT characteristics and pathological subtypes of stage Ⅰ invasive non-mucinous lung adenocarcinoma
摘要
Abstract
Objective:To investigate the correlations between CT characteristics and pathological subtypes in stage Ⅰ invasive non-mucinous lung adenocarcinoma,thereby providing imaging evidence for clinical decision-making.Methods:This retrospective study analyzed clinical and CT data from 143 patients with stage Ⅰ invasive non-mucinous lung adenocarcinoma.Patients were stratified into low-risk(46 cases),medium-risk(67 cases),and high-risk(30 cases)groups.Univariate analysis was used to compare the clinical parameters and CT features across groups,followed by multivariate analysis of significant variables.ROC curve analysis was used to evaluate the diagnostic performance of CT features.Results:There was statistically significant differences in lesion density,pulmonary vascular abnormalities,consolidation-to-tumor ratio(CTR),and non-contrast CT value among the three groups(all P<0.001),while no significant differences were found in the lesion size,lobulation,spiculation,vacuole sign,bronchial abnormalities,or pleural traction sign(all P>0.05).Multivariate logistic regression analysis showed that non-contrast CT value was the independent risk factor for distinguishing between low-risk and medium-risk groups(P=0.004),and between low-risk and high-risk groups(P=0.001).And the high-risk group demonstrated significant association with vascular abnormalities compared to the low-risk group,and the vascular abnormality was the independent risk factor for high-risk group(P=0.009).ROC curve analysis confirmed superior diagnostic performance of non-contrast CT value in subtype differentiation.Conclusions:CT characteristics demonstrate significant diagnostic value in distinguishing pathological subtypes of stage Ⅰ invasive non-mucinous lung adenocarcinoma,providing valuable imaging references for clinical management.关键词
肺腺癌/体层摄影术,X线计算机/病理亚型Key words
Lung adenocarcinoma/Tomography,X-ray computed/Pathological subtype引用本文复制引用
王倩,王蓉,解丙坤..Ⅰ期浸润性非黏液性肺腺癌的CT特征与病理亚型的相关性研究[J].中国中西医结合影像学杂志,2025,23(2):223-227,5.基金项目
山东省医药卫生科技发展计划项目(202209011090). （202209011090）
