中国中药杂志2025，Vol.50Issue(5)：1179-1186,8.DOI:10.19540/j.cnki.cjcmm.202411214.102
含铁矿物药赭石和禹余粮的矿物学研究
Mineralogical studies on iron-containing mineral medicines,Haematitum and Limonitum
摘要
Abstract
Haematitum and Limonitum are two iron-containing mineral medicines included in the 2020 edition of the Chinese Pharmacopoeia.They have similar main components and major differences in their property,flavor,channel tropism,and clinical uses.In this study,we investigated the surface properties,mineral composition,mineral dissociation,elemental composition,and iron state of Haematitum and Limonitum to explore their mineralogical differences.Scanning electron microscopy(SEM),specific surface and porosity analyzer,X-ray diffractometer(XRD),X-ray photoelectron spectrometer(XPS),and advanced mineral identification and characterization system(AMICS)were used to analyze the mineralogy of Haematitum and Limonitum.The results showed that Haematitum had an angular surface with granular attachments and a specific surface area of 17.04 m2·g-1.In comparison,Limonitum had a smooth and flat surface with a bundled acicular crystal structure and a specific surface area of 46.29 m2·g-1.Haematitum consists of 31 detectable minerals containing 18 elements,with the major element,iron(44.5％Fe2+and 55.5％Fe3+)distributed in 17 minerals,including hematite,iron oxide,knebelite,siderite,and magnesioferrite.Limonitum consists of 32 detectable minerals containing 17 elements,with the major element,iron(14.5％Fe2+and 85.5％Fe3+)distributed in 19 minerals,including limonite,iron oxide,chlorite,and knebelite.In summary,the elemental composition of Haematitum and Limonitum does not differ greatly,but there are large differences in the mineral composition and iron state.The large specific surface area and strong adsorption capacity of Limonitum may be one of the mechanisms of its anti-diarrheal action.The Fe2O3 and illite contained in Haematitum and Limonitum may be the key substances for their hemostasis effects.The mineralogical differences are expected to provide a reference for explaining the scientific connotation of mineral medicine and laying a material foundation for studying its mechanism of action.关键词
赭石/禹余粮/含铁矿物药/矿物学/矿物自动定量分析系统Key words
Haematitum/Limonitum/iron-containing mineral medicine/mineralogy/advanced mineral identification and charac-terization system(AMICS)引用本文复制引用
卢闵,王晓飞,王程程,陈敬旭,朱航洁,李娟,曹艳..含铁矿物药赭石和禹余粮的矿物学研究[J].中国中药杂志,2025,50(5):1179-1186,8.基金项目
湖北省科技厅重点项目(2023AFD119) （2023AFD119）
