中国中药杂志2025，Vol.50Issue(5)：1224-1230,7.DOI:10.19540/j.cnki.cjcmm.20241216.201
地胆草中1个新的三萜
A new triterpenoid from Elephantopus scaber
摘要
Abstract
The chemical constituents of the petroleum ether extract derived from the 90％ethanol extract of Elephantopus scaber were investigated.By silica gel column chromatography,C18,MCI column chromatography and semi-preparative high performance liquid chromatography,ten compounds were isolated.Their structures were identified as 3β-hydroxy-6β,7β-epoxytaraxeran-14-ene(1),3β-hydroxyolean-12-en-28-oic acid(2),D-friedoolean-14-ene-3β,7α-diol(3),3β-hydroxy-11α-methoxyolean-12-ene(4),3β-hydroxyolean-11,13(18)-diene(5),11α-hydroxy-β-amyrin(6),betulinic acid(7),3β-hydroxy-30-norlupan-20-one(8),6-acetonylchelerythrine(9),and 4′,5′-dehydrodiodictyonema A(10)by analysis of the 1D NMR,2D NMR,MS,and IR spectral data.Among them,compound 1 was a new triterpene and other compounds except compounds 2 and 7 were isolated from this plant for the first time.关键词
地胆草/三萜/3β-hydroxy-6β,7β-epoxytaraxeran-14-eneKey words
Elephantopus scaber/triterpenoid/3β-hydroxy-6β,7β-epoxytaraxeran-14-ene引用本文复制引用
丁祖霄,谢红茜,陈林,郝俊杰,罗艳秋,江志勇,徐士奎..地胆草中1个新的三萜[J].中国中药杂志,2025,50(5):1224-1230,7.基金项目
云南省市场监管科学研究计划项目(2022YSJK08) （2022YSJK08）
兴滇英才支持计划项目 （）
云南省科技计划项目重大科技专项生物医药专项(202402AA310030) （202402AA310030）
云南省中医药联合专项重点项目(202101AZ070001-164) （202101AZ070001-164）
云南省教育厅高原特色民族药用植物研究科技创新团队项目 （）
国家中医药管理局高水平中医药重点学科建设项目(Zyyzdxk-2023192) （Zyyzdxk-2023192）
