中国中药杂志2025，Vol.50Issue(6)：1471-1483,13.DOI:10.19540/j.cnki.cjcmm.20241219.301
白芍中鞣酸类成分的药理作用及作用机制
Pharmacological effect and mechanism of tannic acids in Paeoniae Radix Alba
摘要
Abstract
The chemical composition of Paeoniae Radix Alba(PRA)is complex,with primary secondary metabolites including monoterpenoids,tannins,triterpenoids,and flavonoids.In previous studies on the material basis of PRA,it was found that,in addition to the widely studied characteristic monoterpene glycosides,tannic acid components also play an important role in the efficacy of PRA.However,their pharmacological effects have not been thoroughly investigated.This paper reviews the tannic acid components in PRA,including pentagaloyl glucose(PGG),tetragaloyl glucose(TGG),trigaloyl glucose(TriGG),and gallic acid,along with their structures,properties,and characteristics to provide a detailed discussion of their pharmacological activities and related mechanisms,aiming to offer a theoretical basis for the material basis research and clinical application of PRA.关键词
白芍/鞣酸类/结构与性质/药理活性/机制Key words
Paeoniae Radix Alba/tannic acid/structure and property/pharmacological activity/mechanism引用本文复制引用
刁家鑫,郑琪潼,陈孟尧,洪江川,郝敏,冯庆梅,胡军旗,桑夏楠,曹岗..白芍中鞣酸类成分的药理作用及作用机制[J].中国中药杂志,2025,50(6):1471-1483,13.基金项目
国家自然科学基金项目(82274101,82374123) （82274101,82374123）
浙江省自然科学基金项目(LY24H280002) （LY24H280002）
河北省自然科学基金青年项目(H2023108006) （H2023108006）
浙江省新苗计划项目(2024R410A0324) （2024R410A0324）
