浙江中医药大学学报2025，Vol.49Issue(2)：141-145,5.DOI:10.16466/j.issn1005-5509.2025.02.003
从气津血探讨胃"炎-癌"转化全周期病机演变
Complete Period Pathogenesis of Gastric"Inflammation-Cancer"Transformation Discussed from Qi,Fluid and Blood
摘要
Abstract
[Objective]Based on the relationship of Qi,fluid and blood in the Huangdi Neijing,to explore the basic pathogenesis of gastric"inflammation-cancer"transformation,also provide new ideas for the prevention and treatment of gastric cancer and inhibition of gastric"inflammation-cancer"transformation.[Methods]This paper analyzes the evolution of the pathogenesis of the whole cycle of gastric"inflammation-cancer"transformation with the analysis of Huangdi Neijing,Synopsis of the Golden Chamber,General Treatise on the Cause and Symptoms of Diseases and others.It also summarizes the traditional Chinese medical treatment options of modern medical practitioners for different stages of gastric"inflammation-cancer"transformation.[Results]Chronic atrophic gastritis is induced by liver Qi stagnation,spleen-stomach weakness and insufficient fluid over a long period of time.Lacking vital energy,deficiency of fluid and blood stasis,prolonged accumulation of venom,body fluid blocked-blood stasis,stasis-toxin blockage are the key pathogenic mechanisms of gastric"inflammation-cancer"transformation.To intervene in the process of gastric"inflammation-cancer"transformation,it is necessary to emphasize the simultaneous treatment of Qi,fluid and blood.Intervention in the transformation process of gastric"inflammation-cancer"should emphasize on dredging the liver and regulating the Qi in the early stage,benefiting the Qi and strengthening the spleen in the middle stage,nourishing the Yin and activating the blood in the middle and late stages,and benefiting the Qi and resolving the blood stasis and detoxification in the final stage.[Conclusion]The pathogenetic elements of poor Qi,fluid blocked-blood stasis,stasis-toxin blockage play an important role in the evolution of the whole cycle of gastric"inflammation-cancer"transformation.Regulating Qi,tonifying Yin and activating blood circulation,resolving stasis and removing toxins are the basic methods for treating gastric precancerous lesions,and they have achieved good therapeutic effects in clinical practice.关键词
胃"炎-癌"转化/胃癌前病变/慢性萎缩性胃炎/气津血/瘀毒互结/调气养阴活血/化瘀解毒/全周期分类
医药卫生引用本文复制引用
傅宇斐,胥刘一,胡雪琴,梁玮钰,姜涛,张光霁..从气津血探讨胃"炎-癌"转化全周期病机演变[J].浙江中医药大学学报,2025,49(2):141-145,5.基金项目
国家自然科学基金重点项目(82030119) （82030119）
浙江省自然科学基金探索一般项目(LY22H290005) Key Project of the National Natural Science Foundation of China(82030119) （LY22H290005）
General Project of Zhejiang Natural Science Foundation(LY22H290005) （LY22H290005）
