浙江中医药大学学报2025，Vol.49Issue(2)：146-152,7.DOI:10.16466/j.issn1005-5509.2025.02.004
从络病理论探讨多发性硬化的因机证治
Exploring the Pathogenesis and Treatment of Multiple Sclerosis Based on the Theory of Collateral Diseases
摘要
Abstract
[Objective]To explore the etiology,pathogenesis and treatment principles of multiple sclerosis(MS)based on the theory of collateral diseases in traditional Chinese medicine(TCM).[Methods]By analyzing ancient and modern literature on TCM concepts such as"collateral diseases"and"atrophy syndromes",and integrating modern medical research on the biological mechanisms of MS treatment,this study summarizes the approach to diagnose and treat MS based on the theory of collateral diseases,supported by a case example.[Results]The collaterals are the units for the distribution of blood and Qi,which,through the coordination of meridian Qi flow and the balance of nutrient and defensive Qi,plays a role in distributing blood,Qi and body fluids,and nourishing the meridians and viscera.The physiological characteristics of the collaterals determine that they become sites for the invasion,concealment and development of pathogenic factors.Analysis based on the theory of collateral diseases suggests that damp-heat stagnation,essence deficiency and blood stasis in the collaterals are the underlying mechanisms for the complex clinical manifestations of MS.Treatment principles proposed include strengthening the spleen and promoting diuresis to clear dampness,harmonizing the liver and kidneys to nourish the collaterals,and promoting the circulation of Qi and blood to unblock the collaterals.The attached test case belonged to the impotence of liver and kidney deficiency,treated by supplementing the liver and kidney,warm and smooth meridians,and achieved better curative effect.[Conclusion]The theory of collateral diseases,as an important part of the meridian and collateral system in TCM,holds broad prospects in the treatment of neurological diseases.It can provide methods and ideas for the theoretical research and clinical treatment of MS with TCM.关键词
络病理论/多发性硬化/痿证/病因病机/辨证论治/理论探讨/通络法/医案Key words
the theory of collateral diseases/multiple sclerosis/flaccidity syndrome/etiology and pathology/syndrome differentia-tion and treatment/theoretical discussion/collateral-unblocking method/medical records分类
医药卫生引用本文复制引用
张云帆,赵迪,魏竞竞,梁晓,刘红喜,苗丽娜,张雪茹,陈云梦,张允岭..从络病理论探讨多发性硬化的因机证治[J].浙江中医药大学学报,2025,49(2):146-152,7.基金项目
中国中医科学院科技创新工程项目(CI2021A01301) （CI2021A01301）
国家中医药管理局中医药创新团队及人才支持计划项目(ZYYCXTD-C-202007) （ZYYCXTD-C-202007）
中国中医科学院中医药防治脑病传承创新团队(CI2021B006) Science and Technology Innovation Project of China Academy of Chinese Medical Sciences(CI2021A01301) （CI2021B006）
National TCM Administration,Chinese Medicine Innovation Team and Talent Support Project(ZYYCXTD-C-202007) （ZYYCXTD-C-202007）
Inheritance and Innovation Team of Chinese Medicine Prevention and Treatment of Encephalopathy,Chinese Academy of Traditional Chinese Medicine(CI2021B006) （CI2021B006）
