浙江中医药大学学报2025，Vol.49Issue(2)：179-184,196,7.DOI:10.16466/j.issn1005-5509.2025.02.009
补肺益肾方对慢性阻塞性肺疾病稳定期患者肺康复的疗效观察
The Efficacy of Lung and Kidney Supplementation Formula on the Pulmonary Rehabilitation of Stable Patients with Chronic Obstructive Pulmonary Disease
摘要
Abstract
[Objective]To observe the effect of Lung and Kidney Supplementation Formula on pulmonary rehabilitation in COPD patients with lung and kidney deficiency during the stable period.[Methods]A total of fifty-five stable COPD patients meeting the criteria of lung and kidney Qi deficiency diagnosed in Zhejiang Hospital from October 2021 to January 2023 were randomly allocated into either the experimental group(26 patients)or the control group(29 patients).The treatment of control group had regular inhalation and pulmonary rehabilitation exercise training,while the experimental group took Lung and Kidney Supplementation Formula on the base above.Pulmonary function indexes(FEV1,FEV1%,FEV1/FVC),CAT score,cough ability score,cough difficulty ability score,BMI and TCM evidence score were evaluated in the two groups respectively before treatment,at 4 weeks and 8 weeks of treatment,and adverse reactions were monitored.[Results]In comparison to the baseline,both groups showed an increase in FEV1 and FEV1%at 4 weeks and 8 weeks of treatment,a decrease in CAT score and cough difficulty,with statistically significant differences(P<0.05);BMI and cough ability showed no statistically significant differences(P>0.05);there was no statistically significant difference in FEV1/FVC between the treatment groups at 4 weeks(P>0.05),but an increase at 8 weeks,with statistically significant differences(P<0.05).In comparison to the control group,the experimental group demonstrated a notable reduction in CAT scores and cough difficulty at both 4 weeks and 8 weeks of treatment,indicating statistically significant differences(P<0.05);however,no statistically significant differences were observed in FEV1,FEV1%,cough ability or BMI(P>0.05);the experimental group demonstrated a significant increase in FEV1/FVC at 8 weeks of treatment(P<0.05),however,no statistically significant differences was indicated in FEV1/FVC at 4 weeks of treatment(P>0.05).[Conclusion]The Lung and Kidney Supplementation Formula exhibits a synergistic impact on pulmonary rehabilitation in individuals with COPD.关键词
慢性阻塞性肺疾病/肺肾气虚/补肺益肾方/肺功能/慢性阻塞性肺疾病评估测试/咳嗽能力/体质量指数/肺康复Key words
chronic obstructive pulmonary disease/deficiency of lung and kidney Qi/Lung and Kidney Supplementation Formula/pulmonary function/chronic obstructive pulmonary disease assessment test/cough ability/body mass index/pulmonary rehabilitation分类
医药卫生引用本文复制引用
陆晓玲,李宗菊,吴晨,管兵如,钱璐,唐婷玉..补肺益肾方对慢性阻塞性肺疾病稳定期患者肺康复的疗效观察[J].浙江中医药大学学报,2025,49(2):179-184,196,7.基金项目
浙江省中医药科技计划项目(2022ZA003) Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project(2022ZA003) （2022ZA003）
