植物保护学报2025，Vol.52Issue(1)：8-19,12.DOI:10.13802/j.cnki.zwbhxb.2025.2024051
免疫系统介导的共生微生物对昆虫宿主的影响
Impacts of symbiotic microbes on insect hosts mediated by the immune system
摘要
Abstract
Innate immunity is crucial for insects to adapt to complex environments.Knowledge about the insect immune system helps to discover new insecticide targets and provides ideas for the develop-ment of new pest control strategies.Insects recognize pathogens in the environment through pattern rec-ognition receptors,thus activating the innate immune system to remove pathogens.The insect innate im-mune system mainly includes cellular and humoral immunity.The Toll,immune deficiency(IMD),and Janus kinase/signal transducers and activators of transcription(JAK/STAT)pathways are the key signal-ing pathways that regulate insect humoral immunity.However,more and more studies have shown that immune signaling pathways activated by symbiotic microbes also play non-immune roles alongside their immune roles.Among these,the insulin signaling pathway plays a pivotal role in mediating inter-actions between the immune system and host growth and development.This review first introduces the major innate immune signaling pathways and the insulin signaling pathway in insects.It then elaborates on how immune signaling pathways activated by symbiotic microbes influence insect growth and devel-opment,reproduction,pesticide resistance,chemical communication,cell turnover,lifespan,sleep,and energy metabolism,as well as their underlying molecular mechanisms.Finally,future research direc-tions and methodologies are also discussed to provide ideas for revealing the physiological mechanisms linking symbiotic microbes and insect hosts.关键词
共生微生物/免疫系统/生长发育/繁殖/抗药性/化学通信/代谢重编辑Key words
symbiotic microbe/immune system/growth and development/reproduction/pesticide re-sistance/chemical communication/metabolic reprogramming引用本文复制引用
王争艳,张闪,周丽贞,赵亚茹,刘之源..免疫系统介导的共生微生物对昆虫宿主的影响[J].植物保护学报,2025,52(1):8-19,12.基金项目
国家自然科学基金(32272531),河南省科技公关项目(222103810069) （32272531）
