摘要
Abstract
Objective:To analyze the effect of Remifentanil combined with Propofol target controlled infusion anesthesia on patients undergoing nasal endoscopic surgery.Method:A total of 92 patients who underwent nasal endoscopic surgery were admitted to Jinan Integrated Traditional Chinese and Western Medicine Hospital from March 2022 to March 2024.They were randomly divided into two groups,with 46 patients in each group.The observation group received target controlled infusion anesthesia with Remifentanil combined with Propofol,while the control group received intravenous infusion anesthesia with Remifentanil combined with Etomidate.The incidence of agitation,degree of pain,awakening quality,hemodynamics,and adverse reactions between two groups were compared.Result:The incidence of agitation in the observation group was 4.35%(2/46),which was lower than 17.39%(8/46)in the control group,the difference was statistically significant(字2=4.039,P=0.045).At 4 h,12 h and 24 h after operation,visual analogue scale(VAS)scores in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The recovery time of spontaneous respiration,extubation time,eye opening time and postanesthesia care unit(PACU)residence time in the observation group were significantly better than those in the control group,the differences were statistically significant(P<0.05).There were no significant differences in mean arterial pressure(MAP),heart rate(HR)at the end of surgery(T0)between the two groups(P>0.05).At 15 min after extubation(T1),at the time of exit from PACU(T2),MAP and HR in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Remifentanil combined with Propofol target controlled infusion anesthesia can reduce the incidence of agitation in patients undergoing endoscopic sinus surgery,alleviate postoperative pain,and the hemodynamic indicators is better,which can promote patient recovery,and cause no severe adverse reactions.关键词
鼻内镜手术/瑞芬太尼/血流动力学/躁动/不良反应Key words
Nasal endoscopic surgery/Remifentanil/Hemodynamics/Agitation/Adverse reactions
