中药材2024，Vol.47Issue(4)：882-886,5.DOI:10.13863/j.issn1001-4454.2024.04.014
刺猬紫檀心材中两个新天然产物化学成分研究
Study on the Chemical Constituents of Two New Natural Products from Heartwood of Pterocarpus erinaceus
摘要
Abstract
Objective:To study the chemical constituents from the heartwood of Pterocarpus erinaceus.Methods:Silica gel column chromatography,Sephadex LH-20 gel column chromatography and preparative high liquid phase methods were used to isolate and purify the ethyl acetate fraction of ethanol extract of Pterocarpus erinaceus heartwood.The structures of the compounds were identified by spec-troscopic methods.Results:Fifteen compounds were isolated from the ethyl acetate fraction of ethanol extract of Pterocarpus erinaceus he-artwood and identified as 2-(4-methoxyphenyl)propanoic acid(1),1'-(3,4-dihydroxyphenyl)ethanol(2),7,2'-dihydroxy-4',5'-meth-ylenedioxyisoflavan(3),angolensin(4),methyl 2,4-dihydroxybenzoate(5),ethyl 3,4-dihydroxybenzoate(6),biochanin A(7),2,2'-oxybis(1,4-di-tert-butylbenzene)(8),7-hydroxydihydroflavone(9),prunetin(10),resorcinol(11),4'-methoxy-5,6,7-trihydroxyisofla-vone(12),bolusanthin Ⅳ(13),vestitol(14),2-O-methylangolensin(15),respectively.Conclusion:Among them,compounds 1 and 2 are new natural products,compounds 3,12,15 are isolated from Pterocarpus genus for the first time,compounds 5 to 9,11,13,14 are i-solated from Pterocarpus erinaceus for the first time.关键词
刺猬紫檀/化学成分/结构鉴定Key words
Pterocarpus erinaceus Poir./Chemical constituents/Structure identification分类
医药卫生引用本文复制引用
戴兴,朱清,孟晓伟,王艳梅,陈兰英,刘荣华..刺猬紫檀心材中两个新天然产物化学成分研究[J].中药材,2024,47(4):882-886,5.基金项目
江西省自然科学基金项目(20224ACB206043) （20224ACB206043）
国家自然科学基金项目(82160732,81660676,81360629) （82160732,81660676,81360629）
国家重点研发计划项目(2018YFC1706102) （2018YFC1706102）
