遵义医科大学学报2025，Vol.48Issue(3)：270-273,4.
以急性脑梗死起病伴发恶性肿瘤患者的临床特征及相关危险因素分析
Analysis of clinical features and related risk factors in patients with cerebral infarction as the first symptom accompanied by malignant tumor
摘要
Abstract
Objective To explore the clinical features,imaging manifestations,laboratory findings and risk fac-tors of patients with acute cerebral infarction starting with concomitant malignant tumor.Methods Thirty-nine pa-tients with acute cerebral infarction in the Affiliated Hospital of Zunyi Medical University were retrospectively col-lected from August 2019 to December 2023,and divided into the tumor group(19 cases)and the control group(20 cases)according to whether they were accompanied by malignant tumors or not,and analyzed the clinical characteristics and related risk factors of the patients in the two groups.Results Among the 19 patients with cere-bral infarction manifested with malignant tumors,the most common tumor was lung cancer in 13 cases(68.4%),and there were significant differences between the tumor group and the control group in terms of age of onset,male to female ratio,and NIHSS score(P＜0.05).In the control group,most of the diseased vessels were distributed in the anterior circulation,which was significantly different from the tumor group(P＜0.05),and the detection rate of multiple vessels in the anterior and posterior circulation of the patients in the tumor group was higher than that of the control group,which was statistically significant(P＜0.05).The difference in peripheral blood fibrinogen,Neutrophil-to-lymphocyte ratio(NLR)and platelet-to-lymphocyte ration(PLR)be-tween the tumor group and the control group was statistically significant(P＜0.05).Conclusion The most com-mon tumor type in patients with acute cerebral infarction manifestations associated with malignant tumors was lung cancer.More patients with malignant tumors combined with traditional stroke risk factors and systematic tumor screening should be performed in patients with acute multiple cerebral infarctions that do not fit into a single arte-rial supply zone.关键词
脑梗死/肿瘤/恶性/危险因素Key words
cerebral infarction/tumours/malignancy/risk factor分类
临床医学引用本文复制引用
潘成玉,刘草原,梁涛,张霞,郝仁方,徐祖才..以急性脑梗死起病伴发恶性肿瘤患者的临床特征及相关危险因素分析[J].遵义医科大学学报,2025,48(3):270-273,4.基金项目
国家自然科学基金资助项目(NO:82360268). （NO:82360268）
