遵义医科大学学报2025,Vol.48Issue(3):295-306,12.
中西医结合治疗糖尿病肾病的研究进展
Research progress on integrated traditional Chinese and western medicine in the treatment of diabetic kidney disease
摘要
Abstract
Diabetic kidney disease is a serious complication of diabetes,which is the leading cause of end-stage renal disease worldwide.Approximately 40%of individuals with diabetes develop diabetic kidney disease.At present,the most important drugs for diabetic kidney disease include renin-angiotensin-aldosterone system in-hibitors,angiotensin receptor blockers,sodium-glucose cotransporter-2 inhibitors,and newly approved aldoste-rone receptor antagonists.However,to date,there are still no effective drugs to prevent diabetic kidney disease from progressing to end-stage renal disease.Network pharmacology combined with bioinformatics and pharmacol-ogy provides a powerful tool for studying the mechanism of drug action.Traditional Chinese medicine has accu-mulated rich experience in the treatment of diabetic kidney disease,and its multi-target,multi-component,and multi-pathway characteristics provide new ideas for modern medicine.This article reviews the research progress of network pharmacology and drug therapy in diabetic kidney disease.关键词
糖尿病肾病/网络药理学/中医药/终末期肾病Key words
diabetic kidney disease/network pharmacology/traditional Chinese medicine/end-stage renal disease分类
医药卫生引用本文复制引用
罗亚丹,杨宇齐,查艳..中西医结合治疗糖尿病肾病的研究进展[J].遵义医科大学学报,2025,48(3):295-306,12.基金项目
国家自然科学基金资助项目(NO:82360148) (NO:82360148)
贵州省科学技术基金资助项目[NO:贵州省科技基金-ZK(2024)一般679] (2024)
遵义市科技合作项目[NO:HZ(2022)94]. (2022)