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中西医结合治疗糖尿病肾病的研究进展

罗亚丹 杨宇齐 查艳

遵义医科大学学报2025,Vol.48Issue(3):295-306,12.
遵义医科大学学报2025,Vol.48Issue(3):295-306,12.

中西医结合治疗糖尿病肾病的研究进展

Research progress on integrated traditional Chinese and western medicine in the treatment of diabetic kidney disease

罗亚丹 1杨宇齐 2查艳2

作者信息

  • 1. 遵义市第一人民医院,遵义医科大学第三附属医院 肾内科,贵州 遵义 563000
  • 2. 国家卫生健康委员会肺脏免疫性疾病诊治重点实验室,贵州省常见慢性疾病发病机制及防治研究全省重点实验室,贵州省人民医院 肾内科,贵州 贵阳 550002
  • 折叠

摘要

Abstract

Diabetic kidney disease is a serious complication of diabetes,which is the leading cause of end-stage renal disease worldwide.Approximately 40%of individuals with diabetes develop diabetic kidney disease.At present,the most important drugs for diabetic kidney disease include renin-angiotensin-aldosterone system in-hibitors,angiotensin receptor blockers,sodium-glucose cotransporter-2 inhibitors,and newly approved aldoste-rone receptor antagonists.However,to date,there are still no effective drugs to prevent diabetic kidney disease from progressing to end-stage renal disease.Network pharmacology combined with bioinformatics and pharmacol-ogy provides a powerful tool for studying the mechanism of drug action.Traditional Chinese medicine has accu-mulated rich experience in the treatment of diabetic kidney disease,and its multi-target,multi-component,and multi-pathway characteristics provide new ideas for modern medicine.This article reviews the research progress of network pharmacology and drug therapy in diabetic kidney disease.

关键词

糖尿病肾病/网络药理学/中医药/终末期肾病

Key words

diabetic kidney disease/network pharmacology/traditional Chinese medicine/end-stage renal disease

分类

医药卫生

引用本文复制引用

罗亚丹,杨宇齐,查艳..中西医结合治疗糖尿病肾病的研究进展[J].遵义医科大学学报,2025,48(3):295-306,12.

基金项目

国家自然科学基金资助项目(NO:82360148) (NO:82360148)

贵州省科学技术基金资助项目[NO:贵州省科技基金-ZK(2024)一般679] (2024)

遵义市科技合作项目[NO:HZ(2022)94]. (2022)

遵义医科大学学报

2096-8159

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