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A novel model of central precocious puberty disease:Paternal MKRN3 gene-modified rabbit

Bangzhu Chen Xing Ye Lihao Chen Tianping Liu Guiling Li Chula Sa Juan Li Ke Liu Weiwang Gu Gang Wang

Animal Models and Experimental Medicine2025,Vol.8Issue(3):P.511-522,12.
Animal Models and Experimental Medicine2025,Vol.8Issue(3):P.511-522,12.DOI:10.1002/ame2.12544

A novel model of central precocious puberty disease:Paternal MKRN3 gene-modified rabbit

Bangzhu Chen 1Xing Ye 2Lihao Chen 3Tianping Liu 4Guiling Li 5Chula Sa 4Juan Li 5Ke Liu 5Weiwang Gu 4Gang Wang5

作者信息

  • 1. Department of Obstetrics and Gynecology,Guangdong Provincial Key Laboratory of Major Obstetric Diseases,Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology,Guangdong-Hong Kong-Macao Greater Bay Area Higher Education Joint Laboratory of Maternal-Fetal Medicine,The Third Affiliated Hospital,Guangzhou Medical University,Guangzhou,China Guangdong Medical Laboratory Animal Center,Guangdong Provincial People''s Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou,China
  • 2. School of Basic Medical Sciences,Southern Medical University,Guangzhou,China Institute of Comparative Medicine and Laboratory Animal Center,Southern Medical University,Guangzhou,China
  • 3. Department of Obstetrics and Gynecology,Guangdong Provincial Key Laboratory of Major Obstetric Diseases,Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology,Guangdong-Hong Kong-Macao Greater Bay Area Higher Education Joint Laboratory of Maternal-Fetal Medicine,The Third Affiliated Hospital,Guangzhou Medical University,Guangzhou,China
  • 4. Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine,School of Pharmacy and Food Engineering,Wuyi University,Jiangmen,China
  • 5. Guangdong Medical Laboratory Animal Center,Guangdong Provincial People''s Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou,China
  • 折叠

摘要

关键词

central precocious puberty/gonadotropin inhibiting hormone(GnIH)/gonadotropin releasing hormone(GnRH)/MKRN3/rabbit

分类

医药卫生

引用本文复制引用

Bangzhu Chen,Xing Ye,Lihao Chen,Tianping Liu,Guiling Li,Chula Sa,Juan Li,Ke Liu,Weiwang Gu,Gang Wang..A novel model of central precocious puberty disease:Paternal MKRN3 gene-modified rabbit[J].Animal Models and Experimental Medicine,2025,8(3):P.511-522,12.

基金项目

National Natural Science Foundation of China,Grant/Award Number:82101937 ()

Guangdong Medical Science and Technology Research Fund Project,China,Grant/Award Number:B2024069 ()

Guangzhou Science and Technology Plan Project,China,Grant/Award Number:2024A04J4923 and SL2023A04J02229。 ()

Animal Models and Experimental Medicine

2096-5451

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