动物营养学报2025，Vol.37Issue(3)：1424-1435,12.DOI:10.12418/CJAN2025.122
线粒体自噬与免疫稳态、肠道健康的互联机制及其调控研究进展
Research Progress on Interconnected Mechanisms of Mitophagy with Immune Homeostasis and Gut Health and Its Regulation
摘要
Abstract
Mitophagy is a crucial mechanism within cells for maintaining mitochondrial homeostasis.In recent years,due to its close association with immune homeostasis and gut health,mitophagy has become a focal point in animal nutrition research.Numerous molecular mechanisms regulating mitophagy have been reported,providing new approaches to better understand the process of mitophagy,its role in maintaining mitochondrial function,and overall cellular homeostasis.This paper reviewed the cutting-edge research on the molecular mechanisms of mitophagy,discussed its role and the interconnected pathways between mitophagy and immune homeostasis,gut health,and summarized the current studies on compounds that regulated autophagy.The aim is to offer insights for further research on mitochondria-centered regulatory mechanisms.[Chinese Journal of Animal Nutrition,2025,37(3):1424-1435]关键词
线粒体自噬/分子机制/免疫稳态/肠道健康/分子调控Key words
mitophagy/molecular mechanisms/immune homeostasis/gut health/molecular regulation分类
农业科技引用本文复制引用
杨攀,方梦瑶,田志梅,余苗..线粒体自噬与免疫稳态、肠道健康的互联机制及其调控研究进展[J].动物营养学报,2025,37(3):1424-1435,12.基金项目
国家自然科学基金项目(32372928) （32372928）
广东省基础与应用基础研究基金项目(2024A1515030187) （2024A1515030187）
科技创新战略专项(R2023YJ-YB3006,R2023PY-JX015,R2020YJ-YB2002) （R2023YJ-YB3006,R2023PY-JX015,R2020YJ-YB2002）
广东省乡村振兴战略专项资金(2023TS-3,2023KJ465) （2023TS-3,2023KJ465）
