动物营养学报2025，Vol.37Issue(3)：1470-1479,10.DOI:10.12418/CJAN2025.126
巨噬细胞极化机理及益生菌介导其极化改善肠道健康的研究进展
Research Progress on Mechanism of Macrophage Polarization and Improvement of Intestinal Health Mediated by Probiotics through Macrophage Polarization
摘要
Abstract
Probiotics,serving as high-quality alternatives to antibiotics,play a crucial role in promoting intesti-nal health and enhancing production performance in livestock and poultry.Macrophages,as innate immune cells,are pivotal in phagocytosis,inflammation,and other immune responses.Distinct macrophage phenotypes exhibit various biological functions and are regulated by different factors and mechanisms.Studies have shown that probiotics can mediate macrophage polarization,protect intestinal barriers,alleviate intestinal inflamma-tion,and maintain intestinal homeostasis.Therefore,this paper discusses the mechanisms of macrophage polar-ization and the improvement of host intestinal health through probiotic-mediated macrophage polarization,ai-ming to provide a reference for future research on the regulation of intestinal health in livestock and poultry u-sing probiotics.[Chinese Journal of Animal Nutrition,2025,37(3):1470-1479]关键词
益生菌/巨噬细胞/极化/肠道健康/免疫Key words
probiotics/macrophages/polarization/intestinal health/immunity分类
畜牧业引用本文复制引用
梁坤,秦小霞,杨玲媛,黄兴国..巨噬细胞极化机理及益生菌介导其极化改善肠道健康的研究进展[J].动物营养学报,2025,37(3):1470-1479,10.基金项目
湖南省自然科学基金重点项目(2024JJ3020) （2024JJ3020）
湖南省教育厅科学研究重点项目(24A0153) （24A0153）
