动物营养学报2025，Vol.37Issue(3)：1489-1502,14.DOI:10.12418/CJAN2025.128
原花青素的抗炎作用机制及其在畜禽生产中的应用研究进展
Research Progress on Anti-Inflammatory Mechanisms of Proanthocyanidins and Its Application in Livestock and Poultry Production
摘要
Abstract
Proanthocyanidins(PACs),also known as condensed tannins,are a class of polyphenolic com-pounds that are widely distributed in many plants.In recent years,PACs have attracted wide attention due to their diverse biological activities.Many studies have confirmed the significant role of PACs in regulating the in-flammatory response and promoting the repair of damaged tissues,revealing its outstanding potential as an anti-inflammatory active substance.In vivo and in vitro studies have found that the anti-inflammatory mechanism of PACs involves a variety of different pathways.First of all,PACs can effectively reduce the level of oxidative stress;secondly,PACs have a regulatory effect on the arachidonic acid metabolic pathway;in addition,PACs can also inhibit the inflammatory response by affecting inflammation-related signaling pathways and inducing macrophage polarization.This review aims to review the anti-inflammatory activity,mechanism of action and the latest research progress of PACs in livestock and poultry production,so as to provide reference for the ra-tional and efficient application of PACs in livestock and poultry production.[Chinese Journal of Animal Nutri-tion,2025,37(3):1489-1502]关键词
原花青素/抗炎/机制/畜禽生产/应用Key words
proanthocyanidins/anti-inflammatory/mechanism/livestock and poultry production/application分类
农业科技引用本文复制引用
余爱莹,王振江,方正锋,林森..原花青素的抗炎作用机制及其在畜禽生产中的应用研究进展[J].动物营养学报,2025,37(3):1489-1502,14.基金项目
国家自然科学基金青年项目(32102592) （32102592）
广东省农业科学院科技创新战略专项(高水平农科院建设)(R2019YJ-YB3002) （高水平农科院建设）
国家现代农业产业技术体系建设专项(CARS-18-SYZ12) （CARS-18-SYZ12）
广东省乡村振兴战略专项种业振兴行动项目(2023-NBH-00-003) （2023-NBH-00-003）
