大学化学2025，Vol.40Issue(3)：318-327,10.DOI:10.12461/PKU.DXHX202406089
天然多肽的电化学修饰
Electrochemical Modifications of Native Peptides
摘要
Abstract
The rapid development of peptide therapeutics has sparked interest in the chemical modification of native peptides.Electrochemical modification has emerged as a promising technique,offering distinct advantages over traditional chemical approaches,including mild reaction conditions,high chemo-selectivity,and high atom efficiency,all of which align with the principles of green chemistry.This approach has found widespread applications in organic synthesis,with significant progress observed in recent years regarding its use in the modification of native peptides.In this review,we introduce the latest advancements in the field of electrochemical modifications of native peptides,focusing on experimental protocols,reaction mechanisms and synthetic applications.关键词
肽/电化学/绿色化学/反应机理Key words
Peptide/Electrochemistry/Green chemistry/Reaction mechanism分类
社会科学引用本文复制引用
林子涵,林婉真,陈发杰..天然多肽的电化学修饰[J].大学化学,2025,40(3):318-327,10.基金项目
福州大学本科生科研训练计划项目(30288) （30288）
福州大学科研启动经费(511264) （511264）
福建中医药大学青年科技创新培育计划项目(XQC2024001) （XQC2024001）
